Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… are essential to generate an effective immune response to clear intracellular infections …
review intends to shed light on the molecular mechanisms of the cytokines and their functions and …

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
… either the pro-inflammatory cytokines or the activation of the immune cells upon alarm …
and immune complexes, which can exacerbate the coagulation process. All these mechanisms

Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
… cellular and molecular pathway is proposed for COVID-19. The … an initial immune response
featuring inflammatory cytokinemolecular mediators of the COVID-19 immune response. …

Long-COVID and post-COVID health complications: an up-to-date review on clinical conditions and their possible molecular mechanisms

B Silva Andrade, S Siqueira, WR de Assis Soares… - Viruses, 2021 - mdpi.com
… In addition to the understanding of the immune response to COVID-19, the association of …
macrophages and high levels of pro-inflammatory cytokines in COVID-19 [105]) were related to …

COVID-19 and the role of cytokines in this disease

A Hasanvand - Inflammopharmacology, 2022 - Springer
… The most important goal of this review is to study the role of inflammatory cytokines in COVID-19.
… in the types of adaptive immunity, proinflammatory cytokines, and interleukins and anti-…

Immune response, inflammation, and the clinical spectrum of COVID-19

LF García - Frontiers in immunology, 2020 - frontiersin.org
… viral entrance through canonical viral-receptor pathways, as recently shown for MERS-CoV
(90), thereby activating these cells and inducing the production of proinflammatory cytokines. …

The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

GH Meftahi, Z Jangravi, H Sahraei, Z Bahari - Inflammation Research, 2020 - Springer
COVID-19 patients [4]. Aging is related to increased levels of systemic pro-inflammatory
cytokines … The number of immune cells also changed in COVID-19 infection [29, 30]. Indeed, in …

Humoral immune mechanisms involved in protective and pathological immunity during COVID-19

G Widjaja, AT Jalil, HS Rahman, WK Abdelbasset… - Human Immunology, 2021 - Elsevier
… of the humoral immune response (inflammatory cytokine and immunoglobulin … role of
antibodies in protective immunity and immune pathogenesis of viral diseases, we focus this review

Immune signature of covid-19: In-depth reasons and consequences of the cytokine storm

P Niedźwiedzka-Rystwej, A Majchrzak… - … Journal of Molecular …, 2022 - mdpi.com
COVID-19-CS, we need to look deeply inside its pathogenesis, which is the purpose of this
review. … have consistently elevated levels of proinflammatory cytokines, which may result in …

Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
… narrative review is to describe the state-of-the-art knowledge on the immune system response
in COVID-19 and to underline the main therapeutic strategies and the key role of vaccines. …