Unravelling structure, localization, and genetic crosstalk of KLF3 in human breast cancer

K Khan, S Safi, A Abbas, Y Badshah… - BioMed research …, 2020 - Wiley Online Library
… profile of TPD52, KLF3, miR-… , KLF3, miR-124, and PKCε in breast cancer patients as well
as to predict their possible correlation with clinicopathological characteristics of breast cancer. …

Predicting 3D Structure, Cross Talks, and Prognostic Significance of KLF9 in Cervical Cancer

S Safi, Y Badshah, M Shabbir, K Zahra, K Khan… - Frontiers in …, 2022 - frontiersin.org
… This interaction facilitates the functions of KLF3 and KLF8 in co-… This study also predicted
the possible crosstalk of KLF9 with … in breast cancer by activating Rho-GTPases (54). Our …

Two sides of the same coin: the roles of KLF6 in physiology and pathophysiology

SE Syafruddin, MA Mohtar, WF Wan Mohamad Nazarie… - Biomolecules, 2020 - mdpi.com
… Group 1 consists of KLF3, KLF8 and KLF12, which function … Interestingly, a recent study
has unravelled a novel KLF6 role … healing involve coordinated crosstalk between the injured …

Cross talk of tumor protein D52 (TPD52) with KLF9, PKCε, and MicroRNA 223 in ovarian cancer

K Khan, S Zafar, Y Badshah, NM Ashraf… - Journal of Ovarian …, 2023 - Springer
… predict the tertiary structure and cellular localization along with … of Akt, resulting in a better
prognosis in breast cancer [40]. … KLF3 and KLF14 have been reported to inhibit tumor growth in …

[HTML][HTML] KLF3 transcription activates WNT1 and promotes the growth and metastasis of gastric cancer via activation of the WNT/β-Catenin signaling pathway

Y Li, Y Wang, Q Zou, S Li, F Zhang - Laboratory Investigation, 2023 - Elsevier
… Previous studies have showed that KLF3 is involved in cell growth, 13 differentiation, 14 …
KLF3 is involved in the malignant progression of lung cancer, 16 melanoma, 17 breast cancer, …

Determining KLF14 tertiary structure and diagnostic significance in brain cancer progression

K Zahra, M Shabbir, Y Badshah, JH Trembley… - Scientific Reports, 2022 - nature.com
… , KLF3 and KLF9, was previously reported in breast cancer … us in gaining insight of possible
crosstalk to these genes. … of different subtypes of brain cancer can further unravel the subtype-…

Characterization of Aryl Hydrocarbon receptor and Kruppel-Like-Factor-6 interaction

KL Pereira De Castro - 2021 - utmb-ir.tdl.org
… al18 investigated the human (hAhR) transcription activation domain localization. Using AhR
… Group 1 includes members that interact with transcriptional repressors and includes KLF3, …

[HTML][HTML] KLF3 promotes colorectal cancer growth by activating WNT1

W Shen, L Yuan, B Hao, J Xiang, F Cheng… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
… specific location of the WNT1 promoter identified by KLF3 (… KLF3 in breast cancer, acute
myeloid leukemia, and osteosarcoma, and is thus linked to an inferior prognosis in breast cancer

[PDF][PDF] Association of PKCi variant and its gene expression with breast cancer prognosis

H Shah, K Khan, Y Badshah, JH Trembley, NM Ashraf… - 2022 - academia.edu
… and to understand the cross talk between the genes under study, … The genomic location
of PKC฀ that is3q26.2, is in a … of KLF3 and miR-124 is observed in breast cancer patients. …

PRKCE non-coding variants influence on transcription as well as translation of its gene

K Khan, S Zafar, A Hafeez, Y Badshah, K Shahid… - RNA biology, 2022 - Taylor & Francis
… 'UTR of PRKCE gene, three TFs including CACCC binding factors such as KLF3, MyoD and
… pathogenic contribution of UTR variants and unravelled the potential molecular mechanism. …