Internet of Things (IoT) is a perfect model to embed various objects with sensors, actuators, and processors, which compute and communicateover internet. Smart healthcare system explores the utilities of IoT for life saving telemedicine, remote diagnosis, patientmonitoring and treatment. This paper proposed an IoT based smart healthcare monitoring framework for real time patient supervision by computing biomedical signals. The proposed multilayered framework enhance the utilities of biosensor based data collection and aggregation, it also leads to design a real time efficient decision support system in case of any intensive condition.