… of mRNA and protein levels of BACE1 and Aβ generation[59]. … hand, Aβ itself may stimulate
the transcription of BACE1 and … fluence the cellular level of the enzyme and APP β cleavage. …

… (EEA1), in which more APP was cleaved to produce Aβ prior to BACE1 cleavage. … ) Control
of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription. …

… APP cleaving enzyme 1 (BACE1, also known as β-secretase) and the γ-secretase complex,
which results in the generation of Aβ … transcriptional modifier. Although there are other minor …

… Aβ is not the only target of BACE1. The knowledge of biology and physiology of this enzyme
… increase the expression and the activity of BACE1 through transcriptional, translational and …

… cleaving enzyme-1 (BACE1) is critical in generating Aβ, … ) for APP or its processing enzymes
to reduce toxic Aβ levels (… The Chitosan-PEG-transactivator of transcription complex was …

… The Aβ peptide is produced by amyloidogenic APP process… the transcription of Wnt target
genes to switch APP processing … in the expression of BACE1 enzyme, because overexpression …

… deletion, increases APP cleavage by BACE1 generating the rapid aggregation of Aβ peptides
which … That is the case of BACE1-antisense transcript (BACE1-AS) that can act on miR-761 …

… The fact that BACE1 is one of two important enzymes … rapid increase in transcription, many
transcription factors become … , because BACE1 has a large role in generating Aβ plaques in …

… process is regulated by various enzymes, among which BACE1 and PS1 are the key enzymes
involved in Aβ … can significantly inhibit ERβ transcriptional activity and its response to …

… with increased level of BACE1 in the brain of rabbits[59]. (4) … compared the activities or
levels of these transcription factors in … pathway of APP processing for increased Aβ production; …