… Functionally impaired TR mutants are present in thyroid papillary cancer[J]. J Clin
Endocrinol Metab,2002,87(3):1120-1128. 10 Crescenzi A,Graziano MF,Carosa E,et al. …

… BRAF mutations are also frequent in papillary carcinoma, … Mutated and non-functional
thyroid hormone receptors are … , but other workers find these mutations to be rare. [31,32]. The …

… 为了更进一步加以验证,我们将上述免疫共沉 淀复合物进行质谱鉴定分析,结果发现TR 抗体免
疫复合物中质谱… Functionally impaired TR mutants are present in thyroid papillary cancer[J]. …

… Mice lacking a functional SELENOF were found to develop … of rectal cancer was found to be
42% higher in current smokers … On the other hand, studies have found that impaired glucose …

… 於乳房腺管癌(ductal carcinoma of the breast),胃癌 (gastric cancer) 和黑色素細胞癌(melanoma)…
Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations …

… microenvironment and impair neuronal and glial cell functions, ultimately leading to … cancer
(Han et al., 2021). A study using APP/PS1 mice and SH-SY5Y cells expressing the mutant …

… cancer is dependent on the tumor stage, patient’s condition and the remaining functional
ability of … activation of AFB1 and scavenge electrophilic intermediate capable of mutation.(95) …

… by mutations in some genes. Studies of zebrafish mutants revealed such genes, for example,
the jekyll mutant… The gene mutated in the jekyll mutant is the Ugdh [uridine 5'-diphosphate (…

… Table 1-1 Aberrations of BMP signaling in human tumor, the functional relevance and …
comes from genetic studies of familial tumor syndromes. Mutations of Smad4 and BMPRIA are …

… CDK4/6 inhibitors impair recovery from cytotoxic chemotherapy in … PLA2G16 is a mutant
p53/KLF5 transcriptional target and … Functional genomics in vivo reveal metabolic dependencies …