[PDF][PDF] Genetic origins of lactase persistence and the spread of pastoralism in Africa
A Ranciaro, MC Campbell, JB Hirbo, WY Ko… - The American Journal of …, 2014 - cell.com
In humans, the ability to digest lactose, the sugar in milk, declines after weaning because of
decreasing levels of the enzyme lactase-phlorizin hydrolase, encoded by LCT. However,
some individuals maintain high enzyme amounts and are able to digest lactose into
adulthood (ie, they have the lactase-persistence [LP] trait). It is thought that selection has
played a major role in maintaining this genetically determined phenotypic trait in different
human populations that practice pastoralism. To identify variants associated with the LP trait …
decreasing levels of the enzyme lactase-phlorizin hydrolase, encoded by LCT. However,
some individuals maintain high enzyme amounts and are able to digest lactose into
adulthood (ie, they have the lactase-persistence [LP] trait). It is thought that selection has
played a major role in maintaining this genetically determined phenotypic trait in different
human populations that practice pastoralism. To identify variants associated with the LP trait …
Genetic Origins of Lactase Persistence and the Spread of Pastoralism in Africa
M Campbell - The American Journal of Human Genetics, 2014 - dh.howard.edu
In humans, the ability to digest lactose, the sugar in milk, declines after weaning because of
decreasing levels of the enzyme lactase-phlorizin hydrolase, encoded by LCT. However,
some individuals maintain high enzyme amounts and are able to digest lactose into
adulthood (ie, they have the lactase-persistence [LP] trait). It is thought that selection has
played a major role in maintaining this genetically determined phenotypic trait in different
human populations that practice pastoralism. To identify variants associated with the LP trait …
decreasing levels of the enzyme lactase-phlorizin hydrolase, encoded by LCT. However,
some individuals maintain high enzyme amounts and are able to digest lactose into
adulthood (ie, they have the lactase-persistence [LP] trait). It is thought that selection has
played a major role in maintaining this genetically determined phenotypic trait in different
human populations that practice pastoralism. To identify variants associated with the LP trait …
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