超氧化物歧化酶1-肌萎缩侧索硬化症的认知障碍
I Martinelli, E Zucchi, C Simonini… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… The encoded SOD1 protein is a Cu/Zn superoxide dismutase… cells, SOD1 protein is found
ubiquitously in the cytosol, … demonstrate that SOD1 defects may increase susceptibility to ALS …
ubiquitously in the cytosol, … demonstrate that SOD1 defects may increase susceptibility to ALS …
神经退行性疾病中的线粒体功能障碍: 在疾病发病机理中的作用, 分析策略和治疗前景
… We will also discuss a panel of approaches aimed at mitigating the … Biogenesis, which is
triggered in response to increased cell … SOD1 encodes for CuZn superoxide dismutase, which …
triggered in response to increased cell … SOD1 encodes for CuZn superoxide dismutase, which …
美国哈佛医学院Jing Chen 团队总结氧化应激在视网膜色素上皮变性中的作用
M Maurya, K Bora, AK Blomfield… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
… only demonstrate susceptibility without proven causality, in contrast to monogenic diseases
… such as SOD1 and catalase. Genetic deletion of REV-ERBα in mice decreases transcription …
… such as SOD1 and catalase. Genetic deletion of REV-ERBα in mice decreases transcription …
病理视网膜中的髓鞘细胞器: 普遍存在和在眼部蛋白质稳态维持中的双重作用
MG Yefimova - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… Along with conventional strategies relying upon the intracellular … Park also resulted in increased
susceptibility of RPE to light. … Cu, Zn-SOD1 is one of the main antioxidant enzymes in the …
susceptibility of RPE to light. … Cu, Zn-SOD1 is one of the main antioxidant enzymes in the …
肌萎缩性脊髓侧索硬化的致病机制
Y Hu, W Chen, C Wei, S Jiang, S Li, X Wang… - 中国神经再生研究(英文 …, 2024 - sjzsyj.com.cn
… increased instability caused by demetallation, mutant SOD1 … (eg, SOD1, TDP-43, FUS and
C9ORF72) form intracellular … 4 of the Cu/Zn superoxide dismutase gene: pathological and …
C9ORF72) form intracellular … 4 of the Cu/Zn superoxide dismutase gene: pathological and …
蛋白质合成调节作为肌萎缩侧索硬化和额颞叶痴呆的治疗方法
SE Charif, MF Vassallu, L Salvañal… - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… factors that tend to increase expression of chaperone proteins and/… Under normal conditions,
SOD1 localizes in the cytoplasm … (1993) Mutations in Cu/Zn superoxide dismutase gene are …
SOD1 localizes in the cytoplasm … (1993) Mutations in Cu/Zn superoxide dismutase gene are …
诱导多能干细胞来源运动神经元的治疗机会和挑战: 治疗肌萎缩性侧索硬化/运动神经元疾病患者
MK Jaiswal - 中国神经再生研究(英文版), 2017 - sjzsyj.com.cn
… by gene encoding Cu/Zn-superoxide dismutase (SOD1) and … phenotype accessed by
intense cytoplasmic labelling of glial … In summary, MN transplantation raises hope in patients for …
intense cytoplasmic labelling of glial … In summary, MN transplantation raises hope in patients for …
淀粉样蛋白β 和tau 蛋白超越阿尔茨海默病
M Abyadeh, V Gupta, JA Paulo… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
… -responsive element on the BACE1 gene promoter and leads to increased Aβ processing
in both endothelial cells and macrophages and result in increased levels of Aβ particularly Aβ1…
in both endothelial cells and macrophages and result in increased levels of Aβ particularly Aβ1…