… the potential impact of NLRP3 inflammasome in the progression of … can be used as an
effective therapeutic target for HCC patients. … Role of the NLRP3 inflammasome in cancer[J]. Mol …

… higher expression levels of NLRP3 inflammasome members, such as NLRP3, ASC, CAS-1, …
To date, only very few compounds targeting NLRP3 or CAS-1 have entered clinical trials. RP…

… siRNA therapy. For these reasons, siRNA-based delivery strategies require overcoming
the various biological barriers to reach the target cell/tissue and promote its therapeutic effect. …

… treatment strategies of each of the known therapeutic targets … indicator molecules of NLRP3
inflammasome activation, and … and are often used for cancer therapy. PLGA was previously …

… -1β production and activation of NLRP3 inflammasome, and leading to neuronal damage. …
and AD may help develop new therapeutic targets and chronic stress management options. …

… Ultimately, accumulation of damaged mitochondria can activate NLRP3 inflammasome…
We conclude with potential mitochondria-targeted therapies that may be beneficial for these …

… Myeloid-derived suppressor cells-a new therapeutic target to overcome resistance to cancer
… Blockage of the NLRP3 inflammasome by MCC950 improves anti-tumor immune responses …

… plays a critical role in the Aβ cascade, but also identify several new targets for AD treat- …
may be a novel target of curcumin, providing a potential new therapeutic strategy for treating AD. …

… , lack of attainment of therapeutic concentration of the drug at target tissues/cells, and …
amalgam of numerous different classes of drugs targeting different intervention points of the …

… To overcome this resistance, we screened … cancer cells under tubacin, erastin conditions
and observed the cell death reality comparatively. Methods: The triple negative breast cancer …