… East respiratory syndrome–coronavirus (MERS-CoV), SARS-CoV-2 is the third coronavirus to cause severe respiratory illness in humans, called coronavirusdisease 2019 (COVID-19). …
B Liu, M Li, Z Zhou, X Guan, Y Xiang - Journal of autoimmunity, 2020 - Elsevier
… Given the efficacy of tocilizumab in CRS and the pivotal role of IL-6 in COVID-19, we propose to repurpose tocilizumab to treat severe cases of COVID-19. Regarding its clinical use, we …
P Perrin, N Collongues, S Baloglu… - European Journal of …, 2021 - Wiley Online Library
… All longitudinal data are shown with respect to the date of COVID-19 symptom onset (D0). Red stars denote the days on which levels of cytokinereleasesyndrome-related inflammatory …
C Zhang, Z Wu, JW Li, H Zhao, GQ Wang - International journal of …, 2020 - Elsevier
… a reasonable hypothesis that cytokine storms play an important role in severe COVID-19 cases. Therefore, neutralising key inflammatory factors in cytokinereleasesyndrome (CRS) will …
… immune response characterized by an upregulation of pro-inflammatory cytokines, resembling the clinical and serological features of cytokinereleasesyndrome (CRS). CRS is a life-…
… of these severe manifestations of COVID-19 is cytokinereleasesyndrome (CRS) and its … These syndromes are characterized by an excessive production of inflammatory cytokines (IL-6, …
W Luo, YX Li, LJ Jiang, Q Chen, T Wang… - Trends in pharmacological …, 2020 - cell.com
… respiratory syndromecoronavirus 2 (SARS-CoV-2) infection has indicated that patients with severe coronavirusdisease 2019 (COVID-19) might experience cytokinereleasesyndrome (…
T Waltuch, P Gill, LE Zinns, R Whitney… - The American Journal of …, 2020 - Elsevier
… However, approximately 1 month after the COVID-19 peak in … healthy children with COVID-19 infection confirmed by serologic … with COVID-19 post-infectious cytokinereleasesyndrome. …
… cytokinereleasesyndrome as observed in COVID-19 patients that may require targeting of cytokine pathways, particularly IL-6-… COVID-19, which is a cytokinereleasesyndrome (CRS). …