Aging is a natural and inevitable process in all living organisms, characterized by the
decline of physiological functions and increased susceptibility to age-related diseases (de …

Aging is closely related to the occurrence of human diseases; however, its exact biological
mechanism is unclear. Advancements in high-throughput technology provide new …

Recognizing age as a pivotal risk factor for age-associated diseases, particularly
neurodegenerative diseases (ND), such as Alzheimer's disease (AD)(Peng et al., 2021) and …

Significance: Aging is a complex trait that is influenced by a combination of genetic and
environmental factors. Although many cellular and physiological changes have been …

Organ degeneration refers to the gradual decline in organ function and structure
deterioration that occurs during aging, which represents the greatest risk factor for various …

Background Given the arrival of the aging population has caused a series of social and
economic problems, we aimed to explore the key genes underlying cognitively normal brain …

Aging is associated with a progressive decline in physiological capacities and an increased
risk of aging-associated disorders. An increasing body of experimental evidence shows that …

Discovering the biological basis of aging is one of the greatest remaining challenges for
biomedical field. Work on the biology of aging has discovered a range of interventions and …

Aging is inevitable, and several structural and functional changes occur in the body with
advanced aging. Aging affects the brain in a variety of ways, the most obvious of which are …

The prevalence of aging-related neuronal diseases is increasing. However, there is still a
huge unmet need for diagnosis, treatments, and drug discovery of these diseases. With the …