慢性腎臟病的病程持續進展, 最後終究會演變為慢性腎衰竭或末期腎臟疾病,
並會造成比正常人多出十到二十倍的心血管併發症發生率. 在慢性腎衰竭的患者中 …

Chronic kidney diseases always develop to chronic renal failure (CRF) or end-stage renal
diseases eventually, and associated with 10 to 20-fold increased incidence in …

Background It has been suggested that the antioxidant properties of olmesartan (OLM), an
angiotensin II type 1 receptor (AT 1 R) blocker, contribute to renal protection rather than …

BACKGROUND AND PURPOSE ApolipoproteinE‐deficient [apoE (−/−)] mice, a model of
human atherosclerosis, develop endothelial dysfunction caused by decreased levels of nitric …

Advanced glycation end products inhibit de novo protein synthesis and induce TGF-β
overexpression in proximal tubular cells. Background We have shown previously that OPB …

Objective To test the hypothesis that advanced glycosylation end products (AGEs) increase
cellular inflammation in atherosclerotic plaques. Methods Fifty rabbits were randomly …

Background Advanced glycation end products (AGEs) are pathogenic factors of diabetic
nephropathy (DN), causing renal damage in various ways. The aim of this study is to …

Advanced glycation end products (AGE) are stable compounds produced by spontaneous
non-enzymatic reaction between reducing sugars and proteins, and have been proven …

背景: 大量增加果糖攝取量會導致高血壓, 胰島素阻抗及脂質異常, 這三者對於心血管疾病皆為已
確立的危險因子. 果糖亦可能造成醣化最終產物(advanced glycation end-product, AGE) 形成 …