Aging entails gradual functional decline influenced by interconnected factors. Multiple
hallmarks proposed as common and conserved underlying denominators of aging on the …

Discovering the biological basis of aging is one of the greatest remaining challenges for
biomedical field. Work on the biology of aging has discovered a range of interventions and …

Organismal aging is driven by interconnected molecular changes encompassing internal
and extracellular factors. Combinational analysis of high-throughput 'multi-omics' datasets …

Organism aging occurs at the multicellular level; however, how pro-longevity mechanisms
slow down aging in different cell types remains unclear. We generated single-cell …

Ageing is a multifactorial process associated with multiple mechanisms, some of which
include telomere shortening, changes in metabolism associated with disrupted …

Diverse individuals age at different rates and display variable susceptibilities to tissue aging,
functional decline and aging-related diseases. Centenarians, exemplifying extreme …

Aging is a complex process that accompanied by molecular and cellular alterations. The
identification of tissue-/cell type-specific biomarkers of aging and elucidation of the detailed …

The exponential scientific and technological progress during the past 30 years has favored
the comprehensive characterization of aging processes with their multivariate nature …

Aging is a natural and inevitable process in all living organisms, characterized by the
decline of physiological functions and increased susceptibility to age-related diseases (de …

Understanding the biological mechanisms behind aging, lifespan and healthspan is
becoming increasingly important as the proportion of the world's population over the age of …