耐药性是乳腺癌治疗的重大挑战之一. 有多种原因和机制导致乳腺癌耐药的发生.
外泌体及其内容物(DNA, mRNA, 蛋白质, 非编码RNA 等) 是细胞间通讯的重要介质 …

Drug resistance is a major challenge in the treatment of breast cancer. Many causes and
mechanisms lead to the occurrence of drug resistance in breast cancer. Exosomes and their …

Breast cancer (BC) ranks first among female malignant tumors and involves hormonal
changes and genetic as well as environmental risk factors. In recent years, with the …

Breast cancer (BC) is the most common malignancy among women worldwide. Like many
other cancers, BC therapy is challenging and sometimes frustrating. In spite of the various …

研究提示外泌体通过分泌各种信号分子参与乳腺癌发展及治疗过程, 乳腺癌在侵袭转移过程中
缺乏可重复性高且可靠的特异性肿瘤标志物, 治疗上仍受药物毒性, 治疗耐药等因素的限制 …

Adriamycin and docetaxel are two agents commonly used in treatment of breast cancer, but
their efficacy is often limited by the emergence of chemoresistance. Recent studies indicate …

Background. Chemoresistance poses a great hindrance in the treatment of breast cancer
(BC). Interestingly, exosome (Exo)‐mediated transfer of long noncoding RNAs (lncRNAs) …

The drugresistance caused by the long-term application of chemotherapeutic drugs is still
the obstacle and problem of current tumor treatment. Therefore, elucidating the mechanism …

Tumor drug resistance is a major challenge in the treatment of cancer. Noncoding RNAs
(ncRNA) play a role in the progression of drug resistance. Recent studies have indicated …

Abstract Development of the acquired resistance is one major obstacle during
chemotherapy for cancer patients. Exosomes mediate intercellular communication and …