The search for reliable and easily accessible biomarkers in Parkinson's disease is receiving
a growing emphasis, to detect neurodegeneration from the prodromal phase and to enforce …

The search for reliable and easily accessible biomarkers in Parkinson's disease is receiving
a growing emphasis, to detect neurodegeneration from the prodromal phase and to enforce …

Parkinson's Disease (PD) is a common neurodegenerative disease which manifests with
motor features, such as bradykinesia, resting tremor, rigidity, and postural instability. Using …

Objective To investigate molecular biomarkers of a‐synuclein and tau aggregation,
autophagy, and inflammation in the saliva of de novo Parkinson's disease (PD) patients in …

Parkinson's disease (PD) diagnosis is still vulnerable to bias, and a definitive diagnosis
often relies on post-mortem neuropathological diagnosis. In this regard, alpha-synuclein …

Introduction Lewy bodies are the pathological hallmarks of Parkinson's disease. There is a
need for effective biomarker that is cost effective, less invasive, and easily reproducible with …

Extracellular plaques composed of the hydrophobic peptide amyloid-β and intraneuronal
accumulation of the hyperphosphorylated protein tau (p-tau) are pathological hallmarks …

The identification of reliable biomarkers of Parkinson's disease (PD) is a pivotal step in the
introduction of causal therapies. Saliva is a biofluid which may be involved in synuclein …

The search for a reliable, early-disease biomarker for Parkinson's disease (PD) that reflects
underlying pathology is a high priority in PD research. Salivary alpha-synuclein (α-Syn) is an …

In Parkinson's disease (PD), alpha-synuclein (a-syn) can be detected in biological fluids
including saliva. Although previous studies found reduced a-syn total (a-syntotal) …