肿瘤包含具有干细胞特性的功能细胞亚群, 称为肿瘤干细胞(cancer stem cell, CSC),
这些细胞亚群在肿瘤的发生和发展中起重要作用. 长链非编码RNA (long non-coding RNA …

Background Tumors contain a functional subpopulation of cells that exhibit stem cell
properties. These cells, named cancer stem cells (CSCs), play significant roles in the …

Long non-coding RNAs (lncRNAs) are a novel class of gene regulators playing multifaceted
roles in physiological processes as well as pathological conditions such as cancer. Cancer …

Cancer is one of the leading causes of death worldwide, primarily due to the dearth of
efficient therapies that result in long-lasting remission. This is especially true in cases of …

Radiotherapy is a well-established therapeutic regimen applied to treat at least half of all
cancer patients worldwide. Radioresistance of cancers or failure to treat certain tumor types …

Cancer stem cells (CSCs) are a cellular subpopulation accelerating cancer cell growth,
invasion and metastasis and survival. After chemoradiotherapy, CSCs are enriched because …

Over the past two decades, cancer stem cells (CSCs) have emerged as an immensely
studied and experimental topic, however a wide range of questions concerning the topic still …

Emerging evidence showed that long non-coding RNAs (lncRNAs) play important roles in a
wide range of biological processes and dysregulated lncRNAs are involved in many …

Decades of research have investigated the mechanisms that lead to the origin of cancer,
striving to identify tumor-initiating cells. These cells, also known as cancer stem cells, are …

In recent years, it has been evidenced that the human transcriptome includes several types
of non-coding RNAs (ncRNAs) that are mainly involved in the regulation of different cellular …