细胞衰老作为生物学界研究的一大热点, 其与正常胚胎发育, 机体老化, 衰老相关疾病等都有着
密切的联系. 近些年来, 对细胞衰老的研究越来越深入, 其发挥的生物学作用也越来越受到重视 …

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细胞衰老被认为是一种细胞生长周期停滞状态, 它不可逆转. 细胞衰老研究是衰老机制和抗衰老,
抗癌研究的重要内容. 目前, 文献中使用的衰老细胞模型和检测指标不尽相同, 尚无统一标准 …

Since its first description over 50 years ago, cellular senescence has gained increasing
attention. The number of research publications on cellular senescence last year alone is …

衰老是生物界的普遍现象, 对多细胞有机体来说, 由受精卵开始, 通过不断分裂和逐级分化出执行
不同功能的细胞, 这些细胞从产生时始, 就处在渐行衰老的过程中, 直至死亡 …

Cellular senescence is a complex and multistep biological process which cells can undergo
in response to different stresses. Referring to a highly stable cell cycle arrest, cellular …

Cellular senescence is the irreversible growth arrest of individual mitotic cells, which as a
consequence display a radically altered phenotype that is thought to impair tissue function …

概述了衰老及相关病变与细胞信号转导障碍或异常的密切关系. 细胞与细胞间或细胞与环境间
无时无刻不在进行着信息联系, 信号转导途径的任何一个环节出现问题, 都可引起细胞生长失控 …

Cellular senescence is implicated in several pathological responses in the adult, with
important repercussions in tumor suppression, wound healing, and aging. Two studies by …