Development of the civilization and medicine enables an even longer lifespan of people. To
modulate the aging process it is necessary to discover its molecular mechanism and its …

New and stimulating results have challenged the concept that cellular senescence might not
be synonymous with aging. It is indisputable that during aging, senescent cell accumulation …

Why do we grow old: is it because our cells just wear out, we run out of cells (or both), and what
can we do about it? | Longevity & Healthspan Skip to main content SpringerLink Account Menu …

SnapShot: Cellular Senescence in Pathophysiology Page 1 Lysosomal activity SASP SASP
Immune surveillance Cellular plasticity/ tissue regeneration Cellular plasticity/tissue regeneration …

Cellular senescence is a fundamental process that may play positive or detrimental roles for
the organism. It is involved in tissue development and in tumor prevention although during …

Cellular senescence is the arrest of normal cell division. Oncogenic genes and oxidative
stress, which cause genomic DNA damage and generation of reactive oxygen species, lead …

Given the duration of ageing in humans, cell culture studies are a promising approach to the
study of human ageing. It is reasonable to assume that human ageing has, at least partly, a …

Senescence is a form of cellular aging that limits the proliferative capacity of cells.
Senescence can be triggered by different stress stimuli, such as DNA damage or oncogene …