Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study

AJC Slooter, P de Knijff, A Hofman, M Cruts… - Neuroscience …, 1998 - Elsevier
The APOE* 4 allele of the apolipoprotein E gene (APOE) is an important risk factor for
Alzheimer's disease. It has been suggested that levels of apolipoprotein E (apoE) in plasma …

Apolipoprotein E genotype and progression of Alzheimer's disease: the Rotterdam Study

AJC Slooter, JJ Houwing-Duistermaat… - Journal of …, 1999 - Springer
The APOE* 4 allele of the apolipoprotein E gene increases the risk of Alzheimer's disease
(AD), but whether it also affects the course of the disease is controversial. However, all …

Apolipoprotein E polymorphism and serum concentration in Alzheimer's disease in nine European centres: the ApoEurope study

G Siest, P Bertrand, B Qin, B Herbeth, JM Serot… - 2000 - degruyter.com
As part of the ApoEurope Project, apolipoprotein E (apo E) common polymorphism and
serum concentration were determined in 489 Alzheimer's disease patients and 429 controls …

Plasma levels of apolipoprotein E and genetic markers in elderly patients with Alzheimer's disease

R Scacchi, G Gambina, M Ruggeri, MC Martini… - Neuroscience …, 1999 - Elsevier
Besides apolipoprotein E (APOE) polymorphism, whose association with Alzheimer's
disease (AD) has been confirmed in most of the numerous population samples studied …

Apolipoprotein E (APOE) polymorphism influences serum APOE levels in Alzheimer's disease patients and centenarians

F Panza, V Solfrizzi, AM Colacicco, AM Basile… - …, 2003 - journals.lww.com
Vascular factors may play a role in the etiology of Alzheimer's disease (AD) and increased
serum apolipoprotein E (APOE) levels in AD could be of interest, as APOE concentration is …

Apolipoprotein E (apoE) polymorphism and its influence on ApoE concentrations in the cerebrospinal fluid in Finnish patients with Alzheimer's disease

T Lehtimäki, T Pirttilä, PD Mehta, HM Wisniewski… - Human genetics, 1995 - Springer
The apoE phenotype of 83 patients with probable Alzheimer's disease (AD) and of 164 non-
demented controls was determined by isoelectric focusing and Western blotting. The …

Frequency of the apolipoprotein E ε2 allele is diminished in sporadic Alzheimer disease

HL West, GW Rebeck, BT Hyman - Neuroscience letters, 1994 - Elsevier
Recent data have demonstrated genetic disequilibrium between inheritance of the
apolipoprotein E (apoE) ε4 allele and increased risk of Alzheimer disease. We tested the …

Apolipoprotein E (apoE) levels in brains from Alzheimer disease patients and controls

T Pirttilä, H Soininen, O Heinonen, T Lehtimäki… - Brain research, 1996 - Elsevier
We measured apolipoprotein E (apoE) level in neutral and acidic pH extracts of the frontal,
temporal and cerebellar cortices from patients with definite Alzheimer's disease (AD) and …

Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease

A Merched, H Blain, S Visvikis, B Herbeth… - Journal of the …, 1997 - Elsevier
Worldwide evidence has recently shown that the allele œ4 of apolipoprotein E (ApoE) is a
genetic risk factor for Alzheimer's disease (AD) underlining the possible role of apoE in the …

Lack of association between apolipoprotein E allele ɛ4 and sporadic Alzheimer's disease

L Lannfelt, L Lilius, M Nastase, M Viitanen… - Neuroscience …, 1994 - Elsevier
Apolipoprotein E (apoE) is a protein involved in the transport of lipids and a component of
Alzheimer's disease (AD) plaques. There are three common alleles of the apoE gene …