[HTML][HTML] Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins

KS Montine, CN Bassett, JJ Ou, WR Markesbery… - Journal of lipid …, 1998 - ASBMB
The major apolipoproteins (apo) on human cerebrospinal fluid lipoproteins are apoA-I and
apoE. Given the association between inheritance of the ε4 allele of the apoE gene (APOE4) …

Apolipoprotein E polymorphism and susceptibility to Alzheimer's disease

MI Kamboh - Human Biology, 1995 - JSTOR
Apolipoprotein E (apoE, protein; APOE, gene) plays an important role in lipoprotein
metabolism by acting as a ligand for two specific cell receptors to mediate the uptake of …

Novel large apolipoprotein E‐containing lipoproteins of density 1.006–1.060 g/ml in human cerebrospinal fluid

JR Guyton, SE Miller, ME Martin… - Journal of …, 1998 - Wiley Online Library
Although the critical role of apolipoprotein E (apoE) allelic variation in Alzheimer's disease
and in the outcome of CNS injury is now recognized, the functions of apoE in the CNS …

Apolipoprotein E genotype affects size of ApoE complexes in cerebrospinal fluid

NM Heinsinger, MA Gachechiladze… - … of Neuropathology & …, 2016 - academic.oup.com
Apolipoprotein E (apoE) is associated with lipoproteins in the cerebrospinal fluid (CSF).
APOE4 increases and APOE2 decreases the risk for Alzheimer disease (AD) compared to …

Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice

RB DeMattos, RP Brendza, JE Heuser… - Neurochemistry …, 2001 - Elsevier
The ε4 allele of apolipoprotein E (apoE) is a genetic risk factor for Alzheimer's disease (AD).
In order to gain a better understanding of the molecular mechanisms by which apoE and …

Association between apolipoprotein E polymorphism and serum lipid and apolipoprotein levels with Alzheimer's disease

AV Raygani, Z Rahimi, H Kharazi, H Tavilani… - Neuroscience …, 2006 - Elsevier
We have recently demonstrated that apolipoprotein E (APOE)-ɛ4 allele is a risk factor for
Alzheimer disease (AD) in Tehran, Iran. The current study specifically aimed to examine …

Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study

AJC Slooter, P de Knijff, A Hofman, M Cruts… - Neuroscience …, 1998 - Elsevier
The APOE* 4 allele of the apolipoprotein E gene (APOE) is an important risk factor for
Alzheimer's disease. It has been suggested that levels of apolipoprotein E (apoE) in plasma …

Apolipoprotein E in cerebrospinal fluid from patients with Alzheimer's disease and other forms of dementia is reduced but without any correlation to the apoE4 isoform

M Landén, C Hesse, P Fredman, B Regland… - Dementia and Geriatric …, 1996 - karger.com
Apolipoprotein E (apoE) has been suggested to play a role in regenerative processes in the
brain after trauma, and also in the pathogenesis of Alzheimer''s disease (AD). We examined …

Brain expression of apolipoproteins E, J, and A‐I in Alzheimer's disease

SD Harr, L Uint, R Hollister, BT Hyman… - Journal of …, 1996 - Wiley Online Library
Inheritance of the ε4 allele of apolipoprotein (apo) E is associated with increased risk of
Alzheimer's disease (AD) and with increased β‐amyloid peptide (Aβ) deposition in the …

Differences in the Aβ40/Aβ42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype

AM Fagan, LH Younkin, JC Morris… - Annals of Neurology …, 2000 - Wiley Online Library
The ε4 allele of apolipoprotein E (ApoE) is a risk factor for Alzheimer's disease (AD). ApoE,
which is important for lipid metabolism, is also a major constituent of cerebrospinal fluid …