Recent data have demonstrated genetic disequilibrium between inheritance of the
apolipoprotein E (apoE) ε4 allele and increased risk of Alzheimer disease. We tested the …

The frequency of the ε4 allele of apolipoprotein E (apoE) is increased in late‐onset and
sporadic forms of Alzheimer's disease (AD). ApoE also binds to β‐amyloid (Aβ) and both …

The ϵ4 allele of apolipoprotein E (apoE) is associated with increased risk for the
development of Alzheimer's disease (AD), possibly due to interactions with the β-amyloid …

Apolipoprotein E (ApoE) plays a key part in lipid metabolism both in the liver, and in the
CNS. To clarify the association of ApoE polymorphism with Alzheimer's disease and …

While the∈ 4 allele of apolipoprotein E (ApoE) has been identified as a risk factor in
Alzheimer's disease (AD), the mechanism by which this risk is conveyed is not understood …

Apolipoprotein E (apoE) was isolated from human cerebrospinal fluid (CSF) from control
individuals and patients with Alzheimer's disease (AD). The purification was performed with …

In October 1992, at the Alzheimer's Disease Research Center Directors' meeting at the
Society for Neurosciences (Anaheim, California), we reported that the apolipoprotein E-E4 …

The E4 allele for the apolipoprotein E gene has been shown to be a significant risk factor for
Alzheimer's disease. The gene is located in a conserved gene cluster on chromosome …

Inheritance of the apolipoprotein E (apo E) ε4 allele has recently been found to be
associated with Alzheimer's disease. We have studied the clinical and neuropathological …

In our studies apolipoprotein E4 (APOE4) is associated with both early-and late-onset
Alzheimer's disease. Alzheimer's patients from West Texas were screened for the APOE4 …