[HTML][HTML] Spatiotemporal multi-omics: exploring molecular landscapes in aging and regenerative medicine

LX Chu, WJ Wang, XP Gu, P Wu, C Gao… - Military Medical …, 2024 - Springer
Aging and regeneration represent complex biological phenomena that have long captivated
the scientific community. To fully comprehend these processes, it is essential to investigate …

Multimodal Omics Approaches to Aging and Age-Related Diseases

Q Ji, X Jiang, M Wang, Z Xin, W Zhang, J Qu, GH Liu - Phenomics, 2024 - Springer
Aging is associated with a progressive decline in physiological capacities and an increased
risk of aging-associated disorders. An increasing body of experimental evidence shows that …

Single-cell omics in ageing: a young and growing field

X He, S Memczak, J Qu, JCI Belmonte, GH Liu - Nature Metabolism, 2020 - nature.com
Organismal ageing results from interlinked molecular changes in multiple organs over time.
The study of ageing at the molecular level is complicated by varying decay characteristics …

Emerging omics approaches in aging research

JS Lorusso, OA Sviderskiy… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Aging is a complex trait that is influenced by a combination of genetic and
environmental factors. Although many cellular and physiological changes have been …

Spatial omics: An innovative frontier in aging research

Y Chen, S Yang, K Yu, J Zhang, M Wu, Y Zheng… - Ageing Research …, 2023 - Elsevier
Disentangling the impact of aging on health and disease has become critical as population
aging progresses rapidly. Studying aging at the molecular level is complicated by the …

[HTML][HTML] Multi-omics studies on aging and age-related diseases

HP Wang, N Basisty, JH Qu, X Wang - Frontiers in Cell and …, 2024 - frontiersin.org
Aging is a natural and inevitable process in all living organisms, characterized by the
decline of physiological functions and increased susceptibility to age-related diseases (de …

How is Big Data reshaping preclinical aging research?

ME Fernandez, J Martinez-Romero, MA Aon, M Bernier… - Lab Animal, 2023 - nature.com
The exponential scientific and technological progress during the past 30 years has favored
the comprehensive characterization of aging processes with their multivariate nature …

MULTIOMIC SYSTEMS ANALYSIS OF LIFESPAN-EXTENDING INTERVENTIONS IN MOUSE TISSUES

K Watanabe, T Wilmanski, P Baloni… - Innovation in …, 2023 - academic.oup.com
Aging is associated with dysregulation of molecular, cellular, and physiological processes.
Nutritional and pharmacological interventions with different postulated modes of action have …

[PDF][PDF] Degeneration Directory: a multi-omics web resource for degenerative diseases

H Yan, C Lu, C Lan, S Wang, W Zhang, Z He… - Protein & …, 2024 - academic.oup.com
Organ degeneration refers to the gradual decline in organ function and structure
deterioration that occurs during aging, which represents the greatest risk factor for various …

[HTML][HTML] The biology of ageing and the omics revolution

L Harries, K Goljanek-Whysall - Biogerontology, 2018 - Springer
Ageing is a multifactorial process associated with multiple mechanisms, some of which
include telomere shortening, changes in metabolism associated with disrupted …