Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Aging is driven by hallmarks fulfilling the following three premises:(1) their age-associated
manifestation,(2) the acceleration of aging by experimentally accentuating them, and (3) the …

At a recent symposium on aging biology, a debate was held as to whether or not we know
what biological aging is. Most of the participants were struck not only by the lack of …

Answering the question as to why we age is tantamount to answering the question of what is
life itself. There are countless theories as to why and how we age, but, until recently, the very …

Are diseases caused by aging? What are the mechanisms of aging? Do all species age?
These hotly debated questions revolve around a unitary definition of aging. Because we use …

Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

With recent rapid progress in research on aging, there is increasing evidence that many
features commonly considered to be mechanisms or drivers of aging in fact represent …

Genetic, environmental, and pharmacological interventions into the aging process can
confer resistance to multiple age‐related diseases in laboratory animals, including rhesus …

Aging is a dynamic, time-dependent process that is characterized by a gradual accumulation
of cell damage. Continual functional decline in the intrinsic ability of living organisms to …

Age is the main risk factor for the prevalent diseases of developed countries: cancer,
cardiovascular disease and neurodegeneration. The ageing process is deleterious for …