《“健康中国2030” 规划纲要》 强调积极推动主动健康以应对人口老龄化挑战,
对个体与群体层面的抗衰老预防控制策略提出更高要求. 衰老受遗传因素和环境暴露的共同影响 …

" Active health" has been emphasized in" Healthy China 2030" in dealing with the
challenges of population aging, so the anti-aging strategies are requires to be more precise …

Clear evidence exists for heritability of human longevity, and much interest is focused on
identifying genes associated with longer lives. To identify such longevity alleles, we …

Recent advances in molecular and genetic epidemiology provide us with tools to explore the
genetic sources of the variability in humans' biological aging. Genome-wide association …

Over the last two decades, aging research has expanded to include not only age-related
disease models, and conversely, longevity and disease-free models, but also focuses on …

After a brief introduction to the background, significance and unique features of the
centenarian population in China, we describe the Chinese Longitudinal Healthy Longevity …

Human longevity is heritable, but genome-wide association (GWA) studies have had limited
success. Here, we perform two meta-analyses of GWA studies of a rigorous longevity …

Genetic studies have bestowed insight into the biological mechanisms underlying inter-
individual differences in susceptibility to (or resistance to) organisms' aging. Recent …

Background: Recent studies investigating longevity have revealed very few convincing
genetic associations with increased lifespan. This is, in part, due to the complexity of …

Genetic factors contribute to human aging and longevity through the modulation of biologic
pathways, but few longevity-gene associations have been replicated to date. Participants in …