Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges

J Deelen, M Beekman, M Capri, C Franceschi… - …, 2013 - Wiley Online Library
Human lifespan variation is mainly determined by environmental factors, whereas the
genetic contribution is 25–30% and expected to be polygenic. Two complementary fields go …

老龄健康影响因素的跨学科研究国际动态

曾毅 - 科学通报, 2011 - cqvip.com
本文从四方面综述并讨论老龄健康跨学科研究的国际新动态与进展:(1) 发达国家高度重视和
不断加强对老龄健康跨学科研究及其研究策略选择;(2) 老龄健康的社会行为和环境影响因素 …

Genetics: Gene Expression

MML LEI, TKW Lee - Encyclopedia of Gerontology and Population Aging, 2022 - Springer
The Gateway to Global Aging Data (https://g2aging. org/) is a data and information platform
developed to facilitate longitudinal and crosscountry analyses on aging, especially those …

[PDF][PDF] Genetics of human age related disorders

I Srivastava, N Thukral, Y Hasija - Успехи геронтологии, 2015 - researchgate.net
Aging is an inevitable biological phenomenon. The incidence of age related disorders
(ARDs) such as cardiovascular diseases, cancer, arthritis, dementia, osteoporosis, diabetes …

Centenarians as extreme phenotypes: an ecological perspective to get insight into the relationship between the genetics of longevity and age-associated diseases

C Giuliani, C Pirazzini, M Delledonne, L Xumerle… - Mechanisms of Ageing …, 2017 - Elsevier
In this review, we address the genetic continuum between aging and age-related diseases,
with particular attention to the ecological perspective. We describe the connections between …

[HTML][HTML] Genetics of aging, health, and survival: dynamic regulation of human longevity related traits

AI Yashin, D Wu, LS Arbeeva, KG Arbeev… - Frontiers in …, 2015 - frontiersin.org
Background: The roles of genetic factors in human longevity would be better understood if
one can use more efficient methods in genetic analyses and investigate pleiotropic effects of …

Genetics of healthy aging and longevity

AR Brooks-Wilson - Human genetics, 2013 - Springer
Longevity and healthy aging are among the most complex phenotypes studied to date. The
heritability of age at death in adulthood is approximately 25%. Studies of exceptionally long …

Genes that Delay Aging

HM Hinterding, J Deelen - Encyclopedia of Gerontology and Population …, 2022 - Springer
The Gateway to Global Aging Data (https://g2aging. org/) is a data and information platform
developed to facilitate longitudinal and crosscountry analyses on aging, especially those …

2013 年全球衰老研究的重要成果概述

何琪杨 - 老年医学与保健, 2013 - cqvip.com
2013年全球衰老研究的重要成果概述-[维普官方网站]-www.cqvip.com-维普网  我的维普 购物车
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Genome-wide association study and linkage analysis of the healthy aging index

RL Minster, JL Sanders, J Singh… - … Series A: Biomedical …, 2015 - academic.oup.com
Abstract Background. The Healthy Aging Index (HAI) is a tool for measuring the extent of
health and disease across multiple systems. Methods. We conducted a genome-wide …