As the global population becomes older, understanding the impact of aging on health and
disease becomes paramount. Recent advancements in multiomic technology have allowed …

To evaluate molecular events associated with the aging process in animal models and
human tissues, microarray analysis is performed at the regional and cellular levels to define …

Aging is characterized by the interlocking decay of biological functions over time.
Microarrays have been successful in elucidating some of the genome-wide changes that …

Abstract By 2050, population aged> 65 years is expected to be more than 2.5 times that of
the population aged 0–4 years. The onset of age-related ailments, such as …

The aging process has been linked to the occurrence of chronic diseases and functional
impairments, including cancer, sarcopenia, frailty, metabolic, cardiovascular, and …

Aging and regeneration represent complex biological phenomena that have long captivated
the scientific community. To fully comprehend these processes, it is essential to investigate …

The mechanisms of aging are described at the molecular, cell, tissue, and systemic levels.
Primary age-dependent molecular lesions activate the cell stress response to compensate …

Diverse individuals age at different rates and display variable susceptibilities to tissue aging,
functional decline and aging-related diseases. Centenarians, exemplifying extreme …

Basal levels of oxidants are indispensible for redox signaling to produce adaptive cellular
responses such as vitagenes linked to cell survival; however, at higher levels, they are …

Aging entails gradual functional decline influenced by interconnected factors. Multiple
hallmarks proposed as common and conserved underlying denominators of aging on the …