KL Lou, HC Chou, YW Tsai, YS Shiau… - Molecular modeling …, 2001 - Springer
Rundown is a generally encountered problem while recording K ATP channel activity with inside-out patches. No assigned structural fragment related to this mechanism has yet been …
The activity of the ATP-sensitive potassium (KATP) channel, whose sensitivity to ATP and ability to permit K+ flux together allow the channel to couple the metabolic state of a cell to its …
J Bruton - The Journal of Physiology, 2010 - ncbi.nlm.nih.gov
In this issue of The Journal of Physiology, Boudreault et al.(2010) present an interesting phenomenon resulting from inactivation or absence of the skeletal muscle surface …
1 The aim of this study was to characterize the KATP channel of intact rat skeletal muscle (rat flexor digitorum brevis muscle). Changes in membrane currents were recorded with two …
A Chadburn, A Grottesi, K Smith, O Moran… - Biophysical Journal, 2012 - cell.com
ATP-sensitive K+(K ATP) channels, comprised of pore-forming K ir 6. x and regulatory SURx subunits, play important roles in many cellular functions. Vascular (K ir 6.1/SUR2B) and non …
The ATP‐sensitive K+ channel (KATP channel) is essential in preventing contractile dysfunctions during exercise and fatigue in skeletal muscle (Cifelli et al. 2007. J. Physiol …
Regulation of pancreatic K ATP channels involves orchestrated interactions of their subunits, Kir6. 2 and SUR1, and ligands. Previously we reported K ATP channel cryo-EM structures in …
K Banas, C Clow, BJ Jasmin… - American Journal of …, 2011 - journals.physiology.org
It has long been suggested that in skeletal muscle, the ATP-sensitive K+ channel (KATP) channel is important in protecting energy levels and that abolishing its activity causes fiber …