To investigate the effect of transfection of hTERT gene into human mesenchymal stem cells
MSCs on their telomerase activity and lifespan. METHODS Human MSCs were transfected …

Objective. To investigate how mesenchymal stem cell (MSC) telomerase activity and life
span changes after introducing the human telomerase reverse transcriptase (hTERT) gene …

To investigate the expression of exogenous human telomerase reverse transcriptase hTERT
in the human mesenchymal stem cells hMSCs and detect the effect of the gene on cellular …

[Objective] To explicate whether the telomerase activity is regulated by human telomerase
reverse transcriptase (hTERT) in human bone marrow mesenchyme stem cells …

Human mesenchymal stem cells (hMSCs) can be readily isolated from bone marrow and
differentiate into multiple tissues, making them a promising target for future cell and gene …

BACKGROUND: Bone marrow stromal cells (BMSCs) lack telomerase activity. Therefore,
cell telomere length gradually shortens while proliferation in vitro, resulting in cellular …

Human bone marrow mesenchymal stem cells (hMSCs) are promising candidates for cell
therapy and tissue engineering. The life span of hMSCs during in vitro culture is limited …

Serum-free mouse embryo (SFME) cells were established by D. Barnes et al., and are
known to be a neural stem cell line, which differentiate into astrocytes upon treatment with …

Human mesenchymal stem cells (hMSCs) are highly desirable cells for bone engineering
due to the inherent multipotent nature of the cells. Unfortunately, there is a high degree of …

In this study, hBMSC were cultured and transfected with eukaryotic expressing plasmid
pCIneo-hTERT encoding hTERT. After selection with G418 to stabilize the transfection …