Human bone marrow stromal cells (hBMSCs) are defined as pluripotent progenitor cells with
the ability to differentiate into osteoblasts, chondrochytes, adipocytes, muscle cells, and …

Several investigations are being done to increase the short lifetime of mesenchymal stem
cells (MSCs). One of the crucial genes involved in the immortalization of MSCs, hTERT …

Regulation of telomerase activity is thought to participate in the cellular response to ionizing
radiation. Epigenetic mechanisms play a role in this regulation, as well as other mechanisms …

Human mesenchymal stem cells (hMSCs) are attractive candidates for tissue engineering
and cell‐based therapy because of their multipotentiality and availability in adult donors …

AIM: human telomerase reverse transcriptase (hTERT) is the catalytic subunit of telomerase,
and hTERT mRNA expression contributes to telomerase activity. We therefore assessed the …

Human bone marrow mesenchymal stem cells (hMSC) represent a population of stem cells
that are capable of differentiation into multiple lineages. However, these cells exhibit …

In order to explore the effects of exogenous human telomerase reverse transcriptase
(hTERT/hTRT/hEST2) on telomeric restriction fragment (TRF), telomerase activity and its …

Human telomerase, a ribonucleoprotein complex consisting of a catalytic subunit (hTERT)
and a RNA template component (TERC), prevents telomere attrition in human embryonic …

Objectives: Previous studies have reported immortalization and tumorigenicity of human
mesenchymal stem cells (hMSCs) transduced with exogenous human telomerase reverse …

Mesenchymal stem cells (MSCs) from bone marrow are capable of self-renewing and
multipotential differentiation. They can be greatly expanded in vitro and be induced to …