Telomerase activity changes during the differentiation of bone marrow mesenchymal stem cells into neuron-like cells
B He, Z Lin, H Tan - Journal of Biomaterials and Tissue …, 2018 - ingentaconnect.com
Mesenchymal stem cells (MSCs) from bone marrow are capable of self-renewing and
multipotential differentiation. They can be greatly expanded in vitro and be induced to …
multipotential differentiation. They can be greatly expanded in vitro and be induced to …
Engineering a humanized telomerase reverse transcriptase gene in mouse embryonic stem cells
Telomerase is expressed in adult mouse, but not in most human, tissues and mouse
telomeres are much longer than those in humans. This interspecies difference of telomere …
telomeres are much longer than those in humans. This interspecies difference of telomere …
Construction of eukaryotic expression vector of human telomerase RNA component and its function
S Ying, J Xiong, H Mai, J Lin, L Jiang… - Military Medical …, 2016 - pesquisa.bvsalud.org
Objective To construct the eukaryotic expression vector of human telomerase RNA
component (hTR) and study its biological function tentatively. Methods hTR Gene was …
component (hTR) and study its biological function tentatively. Methods hTR Gene was …
Mesenchymal stem cells from Chinese Guizhou minipig by hTERT gene transfection
LL Wei, K Gao, PQ Liu, XF Lu, SF Li, JQ Cheng… - Transplantation …, 2008 - Elsevier
INTRODUCTION: To provide standard implemental cells for biomedical research, an
immortalized mesenchymal stem cell (MSC) lineage was established from the bone marrow …
immortalized mesenchymal stem cell (MSC) lineage was established from the bone marrow …
Effects on telomerase activity and associated-protein of hRPE cells by TGF-beta 1.
H Zhao, S Zeng, X Zhu, Z Zuo, Q Zeng… - Yan ke xue bao (2016 …, 2003 - europepmc.org
To investigate the effects on telomerase activity, human telomerase reverse transcriptase
(hTERT) gene and TEP1mRNA of retinal pigment epithelial (RPE) cells were treated by TGF …
(hTERT) gene and TEP1mRNA of retinal pigment epithelial (RPE) cells were treated by TGF …
Cell cycle dependent telomere regulation by telomerase in human bone marrow mesenchymal stem cells
YM Zhao, JY Li, JP Lan, XY Lai, Y Luo, J Sun… - Biochemical and …, 2008 - Elsevier
Human bone marrow mesenchymal stem cells (hMSCs) are a promising source for clinical
stem cell transplantation. However, telomere regulation mechanisms, as one of the possible …
stem cell transplantation. However, telomere regulation mechanisms, as one of the possible …
The use of hTERT-immortalized cells in tissue engineering
M Kassem, BM Abdallah, Z Yu, N Ditzel, JS Burns - Cytotechnology, 2004 - Springer
The use of human telomerase reverse transcriptase (hTERT)-immortalized cells in tissue
engineering protocols is a potentially important application of telomere biology. Several …
engineering protocols is a potentially important application of telomere biology. Several …
Enhanced long-term survival, but no increase in replicative capacity, following retroviral transduction of human cord blood CD34+ cells with human telomerase …
NJ Elwood, XR Jiang, CP Chiu, JS Lebkowski… - …, 2004 - haematologica.org
Overexpression of telomerase reverse transcriptase (hTERT) can immortalize some primary
human mesenchymal cells. We investigated whether retrovirally-mediated expression of …
human mesenchymal cells. We investigated whether retrovirally-mediated expression of …
Cloning of human telomerase catalytic subunit gene promoter and studying on its specific transcriptional activities in human lung cancer cells
T Xiaojun, W Yanping, Z Qinghua… - Zhongguo Fei Ai …, 2004 - search.proquest.com
目的 克隆人端粒酶催化亚单位 (hTERT) 的启动子, 并检测它在多种人肺癌细胞株和人胚肺成
纤维细胞株中的转录活性, 为肺癌靶向性基因治疗的研究奠定基础. 方法 以人胚肾 293 …
纤维细胞株中的转录活性, 为肺癌靶向性基因治疗的研究奠定基础. 方法 以人胚肾 293 …