Differential expression of human telomerase-associated genes in human hematopoietic cells

N Uchida, T Otsuka, H Shigematsu… - Experimental …, 1998 - kyushu-u.elsevierpure.com
Telomerase is a ribonucleoprotein which specifically extends the telomeric strand in an RNA-
templated reaction. Recently, human telomerase-associated proteins have been described; …

Tumor necrosis factor-α inhibits hTERT gene expression in human myeloid normal and leukemic cells

O Beyne-Rauzy, N Prade-Houdellier, C Demur… - Blood, 2005 - ashpublications.org
Telomerase catalytic subunit (hTERT) has been shown to play a critical role not only in
telomere homeostasis but also in cellular survival, DNA repair, and genetic stability. In a …

Cloning, expression of a segment of hTERT gene and detection of telomerase and hTERT by anti-hTERT polyclonal antibody

SA Saleh, JL Sun, Z Chen, JS Huang… - Shi yan Sheng wu …, 2000 - europepmc.org
Telomerase is an important biomarker in cancer cells. It is active in germline cells, most of
cancer tissues and cell lines, but not in most somatic tissues. Telomerase is composed of …

[引用][C] Human Telomerase

김용석 - Experts meeting on Stillen (DA-9601), 2002 - scholarworks.bwise.kr
Human telomerase RNA (hTR), human telomerase catalytic subunit (hTERT) 및 telomerase-
associated protein (TPI) 로 구성된 telomerase 는 telomere 길이 유지및 이에 따른 세포의 …

Influence of basic fibroblast growth factor on the expression of human telomerase reverse transcriptase (hTERT) in epidermal cells

SUN Xiao-yan, LIU Hui-ling… - Jie Fang Jun Yi Xue Za …, 2011 - search.proquest.com
Objective To investigate the expression of human telomerase reverse transcriptase (hTERT)
in epidermal cells and the influence on basic fibroblasts growth factor (bFGF). Methods The …

[PDF][PDF] Human telomerase reverse transcriptase promoter is activated during liver regeneration and hepatocyte proliferation

H Sirma, M Kumar, JK Meena, B Witt, JM Weise… - academia.edu
Abstract Background & Aims. Telomerase activity is non-detectable in healthy human liver
biopsies, but it is up-regulated in most human liver cancers. There is an ongoing debate …

Neoplastic transformation by TERT in FGF-2-expanded human mesenchymal stem cells

E Yamaoka, E Hiyama… - International …, 2011 - spandidos-publications.com
The low percentage of human mesenchymal stem cells (hMSCs) in bone marrow
necessitates their in vitro expansion prior to clinical use in regenerative medicine. We …

Proliferation changes of human epidermal stem cells in response to transfection with human telomerase reverse transcriptase gene

L Wang, D Liu, W Lan, Z Lin… - Chinese Journal of …, 2010 - pesquisa.bvsalud.org
Objective To investigate the changes of human epidermal stem cells after transfected with
human telomerase reverse transcriptase (hTERT) gene. Methods The plasmid pIRES2 …

Characterization of telomerase (HTERT) in solid and hematopoietic cancer cell lines reveals different expression patterns

LS De Holanda, FP Mesquita… - Anticancer …, 2019 - ar.iiarjournals.org
Background/aim: Overexpression of human telomerase reverse transcriptase (hTERT)
allows disordered proliferation and immortality of malignant cells, which has been of interest …

[PDF][PDF] Construction and characterization of human bone marrow-derived mesenchymal stem cells by overexpressing human telomerase gene

C Tovichit, P Kheolamai, S Manochantr… - 2021 - ethesisarchive.library.tu.ac.th
Currently, bone marrow-derived human mesenchymal stem cells (BM-hMSCs) have been
considered a standard source of hMSCs for research and clinical applications. However, the …