Redefining meaningful age groups in the context of disease

N Geifman, R Cohen, E Rubin - Age, 2013 - Springer
Age is an important factor when considering phenotypic changes in health and disease.
Currently, the use of age information in medicine is somewhat simplistic, with ages …

[引用][C] 健康预期寿命研究进展

张仲迎, 汤哲, 冯明 - 中华流行病学杂志, 2009

Assessment of epigenetic clocks as biomarkers of aging in basic and population research

ME Levine - The Journals of Gerontology: Series A, 2020 - academic.oup.com
The Geoscience paradigm suggests that targeting the aging process could delay or prevent
the risk of multiple major age-related diseases, such as cancer, cardiovascular disease …

A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: a cohort study

Z Liu, PL Kuo, S Horvath, E Crimmins, L Ferrucci… - PLoS …, 2018 - journals.plos.org
Background A person's rate of aging has important implications for his/her risk of death and
disease; thus, quantifying aging using observable characteristics has important applications …

[图书][B] Molecular biomarkers of aging

S Davinelli, C Caruso, D Zella, G Scapagnini, S Vasto - 2012 - researchgate.net
In the Western World, the public perception of advanced aging involves the inability to
survive due to chronic diseases and the combined loss of mobility, sensory functions, and …

[引用][C] Decoding aging: examining the non-evolutionary event from an evolutionary perspective

Y Guo, K Xu, J Cai, Z Wang - Science China Life Sciences, 2024 - Springer
In an era marked by increased longevity, a deeper understanding of the older population is
vital. By introducing an overlooked evolutionary perspective on aging, this article challenges …

Associations between differential aging and lifestyle, environment, current, and future health conditions: Findings from Canadian Longitudinal Study on Aging

Y Song, YS Liu, F Talarico, Y Zhang, J Hayward… - Gerontology, 2023 - karger.com
Introduction: An aging population will bring a pressing challenge for the healthcare system.
Insights into promoting healthy longevity can be gained by quantifying the biological aging …

Biomarkers of ageing: Current state‐of‐art, challenges, and opportunities

R Chen, Y Wang, S Zhang, G Bulloch… - MedComm–Future …, 2023 - Wiley Online Library
Given the unprecedented phenomenon of population ageing, studies have increasing
captured the heterogeneity within the ageing process. In this context, the concept of …

Longitudinal phenotypic aging metrics in the Baltimore Longitudinal Study of Aging

PL Kuo, JA Schrack, ME Levine, MD Shardell… - Nature aging, 2022 - nature.com
To define metrics of phenotypic aging, it is essential to identify biological and environmental
factors that influence the pace of aging. Previous attempts to develop aging metrics were …

Measuring biological age using omics data

J Rutledge, H Oh, T Wyss-Coray - Nature Reviews Genetics, 2022 - nature.com
Age is the key risk factor for diseases and disabilities of the elderly. Efforts to tackle age-
related diseases and increase healthspan have suggested targeting the ageing process …