脂肪组织, 系统性炎症和神经退行性疾病

APA Boleti, PHO Cardoso, BEF Frihling… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
Obesity is associated with several diseases, including mental health. Adipose tissue is
distributed around the internal organs, acting in the regulation of metabolism by storing and …

Adipose tissue, systematic inflammation, and neurodegenerative diseases

APA Boleti, PHO Cardoso, BEF Frihling… - Neural Regeneration …, 2023 - journals.lww.com
Obesity is associated with several diseases, including mental health. Adipose tissue is
distributed around the internal organs, acting in the regulation of metabolism by storing and …

The obese brain: mechanisms of systemic and local inflammation, and interventions to reverse the cognitive deficit

V Salas-Venegas, RP Flores-Torres… - Frontiers in Integrative …, 2022 - frontiersin.org
Overweight and obesity are now considered a worldwide pandemic and a growing public
health problem with severe economic and social consequences. Adipose tissue is an organ …

Obesity and neuroinflammation: a pathway to cognitive impairment

AA Miller, SJ Spencer - Brain, behavior, and immunity, 2014 - Elsevier
Obesity is a growing problem worldwide and is associated with a range of comorbidities,
including cognitive dysfunction. In this review we will address the evidence that obesity and …

Obesity-induced neuroinflammation: beyond the hypothalamus

O Guillemot-Legris, GG Muccioli - Trends in neurosciences, 2017 - cell.com
Obesity is now a worldwide health issue. Far from being limited to weight gain, obesity is
generally associated with low-grade inflammation and with a cluster of disorders collectively …

The role of hypothalamic inflammation in diet-induced obesity and its association with cognitive and mood disorders

S Dionysopoulou, E Charmandari, A Bargiota… - Nutrients, 2021 - mdpi.com
Obesity is often associated with cognitive and mood disorders. Recent evidence suggests
that obesity may cause hypothalamic inflammation. Our aim was to investigate the …

From obesity to hippocampal neurodegeneration: pathogenesis and non-pharmacological interventions

TH Lee, S Yau - International journal of molecular sciences, 2020 - mdpi.com
High-caloric diet and physical inactivity predispose individuals to obesity and diabetes,
which are risk factors of hippocampal neurodegeneration and cognitive deficits. Along with …

Hypothalamic inflammation and obesity: a mechanistic review

J Seong, JY Kang, JS Sun, KW Kim - Archives of pharmacal research, 2019 - Springer
Obesity is one of the worldwide prevalent disease caused by the imbalance between food
intake and energy expenditure. Over a 100 years of research demonstrate that …

Regulation and mechanism of hypothalamic inflammation on obesity

H YOU, Z LIN, S QU - Chinese Journal of Endocrinology and …, 2020 - pesquisa.bvsalud.org
Many studies of the etiology and intervention for obesity have gradually focused on the
brain, trying to curb the occurrence of obesity from the source. Hypothalamic inflammation …

Structural brain changes associated with overweight and obesity

E Gómez-Apo, A Mondragón-Maya… - Journal of …, 2021 - Wiley Online Library
Obesity is a global health problem with a broad set of comorbidities, such as malnutrition,
metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. This …