Maintaining Eastern Newts (Notophthalmus viridescens) for Regeneration Research

HG Simon, S Odelberg - Salamanders in Regeneration Research …, 2015 - Springer
Abstract The adult Eastern newt, Notophthalmus viridescens, has long served as a model for
appendage as well as heart muscle regeneration studies. Newt tissues include all major cell …

Gene Manipulation for Regenerative Studies Using the Iberian Ribbed Newt, Pleurodeles waltl

T Hayashi, T Takeuchi - … in Regeneration Research: Methods and Protocols, 2015 - Springer
Newts provide a unique model animal for regenerative studies. An experimental model
system for molecular genetics in newts is needed in order to clarify the mechanisms of …

Could we also be regenerative superheroes, like salamanders?

A Dall'Agnese, PL Puri - BioEssays, 2016 - Wiley Online Library
Development of methods to reawaken the semi‐dormant regenerative potential that lies
within adult human tissues would hold promise for the restoration of diseased or damaged …

Characterizing the regenerative capacity and growth patterns of the Texas blind salamander (Eurycea rathbuni)

WA Vieira, K Anderson… - Developmental …, 2021 - Wiley Online Library
Background Regeneration of complex patterned structures is well described among,
although limited to a small sampling of, amphibians. This limitation impedes our …

Development of Notophthalmus viridescens embryos

PA Khan, RA Liversage - Development, growth & differentiation, 1995 - Wiley Online Library
Although the North American, adult, red‐spotted newt has been an excellent model in the
study of appendage regeneration at the tissue and cell levels, experiments involving …

[HTML][HTML] Studying mechanisms of regeneration in amphibian and reptilian vertebrate models

K Kusumi, RE Fisher - Anatomical record (Hoboken, NJ: 2007), 2012 - ncbi.nlm.nih.gov
Regeneration, or the de novo formation of new organs, is observed in many different classes
of vertebrates (reviewed in Alibardi, 2010). In teleost fishes, regeneration of heart muscle as …

Molecular genetic system for regenerative studies using newts

T Hayashi, N Yokotani, S Tane… - Development …, 2013 - Wiley Online Library
Urodele newts have the remarkable capability of organ regeneration, and have been used
as a unique experimental model for more than a century. However, the mechanisms …

Regenerative capacity in newts is not altered by repeated regeneration and ageing

G Eguchi, Y Eguchi, K Nakamura, MC Yadav… - Nature …, 2011 - nature.com
The extent to which adult newts retain regenerative capability remains one of the greatest
unanswered questions in the regeneration field. Here we report a long-term lens …

Salamanders aid research into mechanisms of non‐canonical organ regeneration for clinical applications

B Yin, X Cui, Y Liu, JF Fei - Medicine Advances, 2024 - Wiley Online Library
Salamanders possess remarkable regenerative capacities for organ regeneration among
tetrapod vertebrates. Previous research has primarily focused on studying the regeneration …

The axolotl model for regeneration and aging research: a mini-review

C McCusker, DM Gardiner - Gerontology, 2011 - karger.com
Although regeneration of tissues occurs in all adult tetrapods, the ability to regenerate
complex structures such as limbs is limited to urodeles (newts and salamanders). Given that …