α-次亞麻油酸抑制硫酸吲哚誘導SV40 MES 13 小鼠腎絲球間質細胞上皮間質轉化相關蛋白表現之研究

沈佩盈 - 中山醫學大學營養學系學位論文, 2019 - airitilibrary.com
美國國家腎臟基金會(The National Kidney Foundation, NKF) 依腎功能衰退程度所提出的腎臟
疾病分期標準, 慢性腎臟病可依腎絲球過濾率的下降區分成一至五期. 隨著病程發展尿毒素逐漸 …

α-次亞麻油酸抑制硫酸?? 酚誘導SV40 MES 13 小鼠腎絲球間質細胞上皮間質轉化相關蛋白表現之研究

沈佩盈 - 2019 - ir.csmu.edu.tw
美國國家腎臟基金會(The National Kidney Foundation, NKF) 依腎功能衰退程度所提出的腎臟
疾病分期標準, 慢性腎臟病可依腎絲球過濾率的下降區分成一至五期. 隨著病程發展尿毒素逐漸 …

[HTML][HTML] Indoxyl sulfate-induced epithelial-to-mesenchymal transition and apoptosis of renal tubular cells as novel mechanisms of progression of renal disease

SH Kim, MA Yu, ES Ryu, YH Jang, DH Kang - Laboratory investigation, 2012 - Elsevier
Indoxyl sulfate (IS), one of the uremic toxins, is regarded to have a substantial role in the
progression of chronic kidney disease (CKD). Epithelial-to-mesenchymal transition (EMT) …

慢性腎病經由硫酸吲哚酚引起脂肪源性間質幹細胞功能不全之研究

杜緣 - 2014 - ir.lib.pccu.edu.tw
Backgrounds: Indoxyl Sulfate (IS) is a protein metabolite in patients with chronic renal
insufficiency. It also is a uremic toxin that has been suggested to promote the progression of …

Indoxyl sulfate induces epithelial-to-mesenchymal transition in rat kidneys and human proximal tubular cells

D Bolati, H Shimizu, Y Higashiyama… - American journal of …, 2011 - karger.com
Abstract Background/Aims: Indoxyl sulfate (IS) is a uremic toxin that accelerates the
progression of chronic kidney disease (CKD). This study aimed to determine if IS induces …

AST-120 ameliorates epithelial-to-mesenchymal transition and interstitial fibrosis in the kidneys of chronic kidney disease rats

D Bolati, H Shimizu, T Niwa - Journal of Renal Nutrition, 2012 - Elsevier
OBJECTIVE: Indoxyl sulfate (IS), a uremic toxin, is a risk factor for progression of chronic
kidney disease (CKD). AST-120 reduces serum IS and delays the progression of CKD. This …

探討MIF 在IS 誘發的EMT 現象所扮演的角色

許詠婷 - 2019 - nckur.lib.ncku.edu.tw
慢性腎臟病(CKD) 是全世界特別是在已開發國家的一種嚴重疾病. 腎臟纖維化的過程中,
腎臟上皮細胞失去其細胞間的黏附能力, 並轉換成間質細胞, 而這個過程稱之為上皮間質轉化 …

Cellular pathways affected by indoxyl sulfate in human proximal tubular cells

J Shin, DH Oh, SH Kim - BIOMEDICAL RESEARCH-INDIA, 2017 - scholarworks.bwise.kr
Indoxyl sulfate (IS) plays a substantial role in chronic kidney disease (CKD) progression, but
there is insufficient understanding of the complex cellular pathways in the kidney. This study …

Indoxyl Sulfate Induces Mesangial Cell Proliferation via the Induction of COX‐2

S Li, S Cheng, Z Sun, H Mungun, W Gong… - Mediators of …, 2016 - Wiley Online Library
Indoxyl sulfate (IS) is one of important uremic toxins and is markedly accumulated in the
circulation of end stage renal disease (ESRD) patients, which might contribute to the …

Indoxyl sulfate induces renal fibroblast activation through a targetable heat shock protein 90‐dependent pathway

S Milanesi, S Garibaldi, M Saio… - Oxidative Medicine …, 2019 - Wiley Online Library
Indoxyl sulfate (IS) accumulation occurs early during chronic kidney disease (CKD)
progression and contributes to renal dysfunction by inducing fibrosis, inflammation, oxidative …