Promising biomarkers of human aging: In search of a multi-omics panel to understand the aging process from a multidimensional perspective

NA Rivero-Segura, OY Bello-Chavolla… - Ageing research …, 2020 - Elsevier
The aging process has been linked to the occurrence of chronic diseases and functional
impairments, including cancer, sarcopenia, frailty, metabolic, cardiovascular, and …

Aging biomarkers: from functional tests to multi‐omics approaches

KS Kudryashova, K Burka, AY Kulaga… - …, 2020 - Wiley Online Library
Aging results in various deleterious changes in the human body that may lead to loss of
function and the manifestation of chronic diseases. While diseases can generally be reliably …

Measuring healthy ageing: current and future tools

N Silva, AT Rajado, F Esteves, D Brito, J Apolónio… - Biogerontology, 2023 - Springer
Human ageing is a complex, multifactorial process characterised by physiological damage,
increased risk of age-related diseases and inevitable functional deterioration. As the …

[HTML][HTML] Molecular and phenotypic biomarkers of aging

X Xia, W Chen, J McDermott, JDJ Han - F1000Research, 2017 - ncbi.nlm.nih.gov
Individuals of the same age may not age at the same rate. Quantitative biomarkers of aging
are valuable tools to measure physiological age, assess the extent of 'healthy aging', and …

Biomarkers of aging

Aging Biomarker Consortium, H Bao, J Cao… - Science China Life …, 2023 - Springer
Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

[HTML][HTML] Aging hallmarks, biomarkers, and clocks for personalized medicine:(re) positioning the limelight

MC Polidori - Free Radical Biology and Medicine, 2024 - Elsevier
The rapidly increasing aging prevalence, complexity, and heterogeneity pose the scientific
and medical communities in front of challenges. These are delivered by gaps between basic …

Molecular and physiological manifestations and measurement of aging in humans

SS Khan, BD Singer, DE Vaughan - Aging cell, 2017 - Wiley Online Library
Biological aging is associated with a reduction in the reparative and regenerative potential
in tissues and organs. This reduction manifests as a decreased physiological reserve in …

Biomarkers of aging for the identification and evaluation of longevity interventions

M Moqri, C Herzog, JR Poganik, J Justice, DW Belsky… - Cell, 2023 - cell.com
With the rapid expansion of aging biology research, the identification and evaluation of
longevity interventions in humans have become key goals of this field. Biomarkers of aging …

A proposed panel of biomarkers of healthy ageing

J Lara, R Cooper, J Nissan, AT Ginty, KT Khaw… - BMC medicine, 2015 - Springer
Background There is no criterion reference for assessing healthy ageing and this creates
difficulties when conducting and comparing research on ageing across studies. A cardinal …

Aging: the reality: biomarkers of aging: from primitive organisms to humans

RN Butler, R Sprott, H Warner, J Bland… - The Journals of …, 2004 - academic.oup.com
Leading biologists and clinicians interested in aging convened to discuss biomarkers of
aging. The goals were to come to a consensus, construct an agenda for future research, and …