Haematopoietic stem cell niches in the bone marrow

C Fielding, S Méndez-Ferrer - Stem cell biology and …, 2022 - api.taylorfrancis.com
During mammalian postnatal life, the bone marrow (BM) is the primary site of
haematopoiesis and haematopoietic stem cell (HSC) maintenance. Although the generation …

Osteohematopoietic stem cell niches in bone marrow

S Wasnik, A Tiwari, MA Kirkland, G Pande - International review of cell and …, 2012 - Elsevier
In adult mammals, maturation of blood and bone cells from their respective progenitors
occurs in the bone marrow. The marrow region contains many progenitor and stem cell …

The Role of Bone Cells in Establishing the Hematopoietic Stem Cell Niche

JY Wu, HM Kronenberg - Osteoimmunology, 2011 - Elsevier
Publisher Summary Among mammalian stem cells, the best characterized are hematopoietic
stem cells (HSCs). Stem cells have the unique properties of self-renewal and multipotency …

Bone marrow niches and tumour cells: lights and shadows of a mutual relationship

V Granata, L Crisafulli, C Nastasi, F Ficara… - Frontiers in …, 2022 - frontiersin.org
The bone marrow (BM) niche is the spatial structure within the intra-trabecular spaces of
spongious bones and of the cavity of long bones where adult haematopoietic stem cells …

Bone marrow niches for skeletal progenitor cells and their inhabitants in health and disease

M Herrmann, F Jakob - Current stem cell research & therapy, 2019 - ingentaconnect.com
The bone marrow hosts skeletal progenitor cells which have most widely been referred to as
Mesenchymal Stem or Stromal Cells (MSCs), a heterogeneous population of adult stem …

Dissecting the bone marrow HSC niches

M Zhao, L Li - Cell research, 2016 - nature.com
Hematopoiesis is maintained by HSCs, which have extensive selfrenewal capacity and
multipotent differentiation potential to reconstitute all hematopoietic lineages. The BM is a …

Mesenchymal progenitors and the osteoblast lineage in bone marrow hematopoietic niches

C Panaroni, Y Tzeng, H Saeed, JY Wu - Current osteoporosis reports, 2014 - Springer
The bone marrow cavity is essential for the proper development of the hematopoietic
system. In the last few decades, it has become clear that mesenchymal stem/progenitor cells …

Vascular Niche in HSC Development, Maintenance and Regulation

S Coşkun, KK Hirschi - Tissue-Specific Stem Cell Niche, 2015 - Springer
Hematopoietic stem cells (HSC) are multi-potent cells that have ability to self-renew and
differentiate to all blood cell lineages. To function properly, HSC are regulated within unique …

Establishment and regulation of the HSC niche: roles of osteoblastic and vascular compartments

S Coskun, KK Hirschi - Birth Defects Research Part C: Embryo …, 2010 - Wiley Online Library
Hematopoietic stem cells (HSC) are multi‐potent cells that function to generate a lifelong
supply of all blood cell types. During mammalian embryogenesis, sites of hematopoiesis …

The Fetal Hematopoietic Niche: Components and Mechanisms for Hematopoietic Stem Cell Emergence and Expansion

H Hirakawa, Y Lee, L Ding - Current Stem Cell Reports, 2022 - Springer
Abstract Purpose of Review Hematopoiesis is the process of generating all blood and
immune cells, which is fueled at the root by self-renewing multipotent hematopoietic stem …