The mechanisms of aging are described at the molecular, cell, tissue, and systemic levels.
Primary age-dependent molecular lesions activate the cell stress response to compensate …

The aging process is considered a universal and inevitable process of physiological decline
associated with a greater vulnerability to disease and death. Efforts to understand aging …

In humans, aging is ineluctable as well as inexorable. That is really mysterious, because
from a biological viewpoint there is no reason why aging should happen. Aging is stranger …

Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive
picture of all the biological aspects of human aging by describing the key mechanisms …

The pace of physiological aging differs much in individuals, thus the tools to measure it
precisely are to be found. Every quantitative trait of the organism, which is known to change …

Aging is a progressive accumulation of molecular damage in nucleic acids, proteins and
lipids. The inefficiency and failure of maintenance, repair and turnover pathways is the main …

The risk of developing chronic illnesses and disabilities is increasing with age. To predict
and prevent aging, biomarkers relevant to the aging process must be identified. This paper …

During the last 40 years, the study of the biological basis of aging has progressed
tremendously, and it has now become an independent and respectable field of study and …

Aging is an inevitable outcome of life, characterized by a progressive decline in tissue and
organ function. At a molecular level, it is marked by the gradual alterations of biomolecules …