Human mesenchymal stem cells (hMSCs) can be readily isolated from bone marrow and
differentiate into multiple tissues, making them a promising target for future cell and gene …

Telomeres cap the ends of eukaryotic chromosomes, masking the end from DNA repair
processes and preventing end-to-end fusions. Telomeres shorten progressively with each …

Human bone marrow mesenchymal stem cells (hMSC) represent a population of stem cells
that are capable of differentiation into multiple lineages. However, these cells exhibit …

Telomerase activity has been suggested to be critically involved in hematopoietic stem cell
(HSC) self-renewal. However, it has been unclear whether human HSCs have telomerase …

To investigate the expression of exogenous human telomerase reverse transcriptase hTERT
in the human mesenchymal stem cells hMSCs and detect the effect of the gene on cellular …

Human bone marrow mesenchymal stem cells (hMSCs) are promising candidates for cell
therapy and tissue engineering. The life span of hMSCs during in vitro culture is limited …

Multipotent mesenchymal stem cells (MSCs) are widely used as seed cells in studies of
tissue engineering and regenerative medicine; however, their clinical application is limited …

BACKGROUND: Human mesenchymal stem cells (hMSCs) become aging and even die
after several passages. Some investigations have shown that telomere has a close …

Abstract Objective: Human Umbilical cord-derived Mesenchymal Stem Cells (hUCMSCs)
are perinatal stem cells differentiating into various germ layer derivatives including neural …

The enzymatic activity of telomerase is important for the extension of the telomere repeat
sequence and overcoming cellular senescence. We generated a conditional transgenic …