Human telomerase, a ribonucleoprotein complex consisting of a catalytic subunit (hTERT)
and a RNA template component (TERC), prevents telomere attrition in human embryonic …

Mesenchymal stem cells (MSCs) represent one of the most promising stem cells for a
number of degenerative conditions due to their multipotency, immunoprivileged properties …

Telomerase-mediated life-span extension enables the expansion of normal cells without
malignant transformation, and thus has been thought to be useful in cell therapies. Currently …

Mesenchymal stem cells (MSCs) from bone marrow are capable of self-renewing and
multipotential differentiation. They can be greatly expanded in vitro and be induced to …

A current focus of my lab is to elucidate the role of telomerase in stem cell maintenance and
tumorigenesis. Human pluripotent stem cells have active telomerase and therefore long …

Telomerase is activated in pluripotent stem cells and the majority of tumors and is postulated
to be necessary for the acquisition of self-renewal and long-term proliferation. Placental …

BACKGROUND: Cell labeling in combination with in vitro MRI imaging can be used to
noninvasively label transplanted neural stem cells (NSCs), thereby exhibiting the existing …

Background: Telomerase, an enzyme complex that adds telomere repeats to the ends of
linear chromosomal DNA, is an important regulator of cellular senescence and replication …

The human adult mesenchymal stem cell (hMSC) does not express telomerase and has
been shown to be the target for neoplastic transformation after transduction with hTERT …

Objective To investigate the changes of human epidermal stem cells after transfected with
human telomerase reverse transcriptase (hTERT) gene. Methods The plasmid pIRES2 …