Microenvironmental regulation of telomerase isoforms in human embryonic stem cells
L Radan, CS Hughes, JH Teichroeb… - Stem cells and …, 2014 - liebertpub.com
Recent evidence points to extra-telomeric, noncanonical roles for telomerase in regulating
stem cell function. In this study, human embryonic stem cells (hESCs) were cultured in 20 …
stem cell function. In this study, human embryonic stem cells (hESCs) were cultured in 20 …
Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells
S Sekulovic, V Gylfadottir, I Vulto… - Blood, The Journal …, 2011 - ashpublications.org
Strategies for expanding hematopoietic stem cells (HSCs) could have significant utility for
transplantation-based therapies. However, deleterious consequences of such manipulations …
transplantation-based therapies. However, deleterious consequences of such manipulations …
[引用][C] Enhanced temolere rejuvenation in pluripotent cells reprogrammed via SCNT relative to iPSCs
S Gao - 第二届全国发育生物学大会论文集, 2014
Characterization and comparison of telomere length, telomerase and reverse transcriptase activity and gene expression in human mesenchymal stem cells and …
BG Jeon, BM Kumar, EJ Kang, SA Ock, SL Lee… - Cell and tissue …, 2011 - Springer
We have characterized and compared the telomere length, telomerase, reverse
transcriptase (RT) activity and expression of genes implicated in cancer and in pluripotency …
transcriptase (RT) activity and expression of genes implicated in cancer and in pluripotency …
Telomerase as a “stemness” enzyme
F Kong, CY Zheng, DW Xu - Science China Life Sciences, 2014 - Springer
Pluripotent or multipotent stem cells are involved in development and tissue homeostasis;
they have the ability to self-renew and differentiate into various types of functional cells. To …
they have the ability to self-renew and differentiate into various types of functional cells. To …
[引用][C] Telomerase activation of bone marrow mesenchymal stem cells.
WHL Wang HaiLian, JXL Ju XiuLi, GW Ge Wei… - 2007
[HTML][HTML] Differentiation capacity of human urine-derived stem cells to retain telomerase activity
Y Shi, G Liu, R Wu, DL Mack, XS Sun… - Frontiers in Cell and …, 2022 - frontiersin.org
Telomerase activity is essential for the self-renewal and potential of embryonic, induced
pluripotent, and cancer stem cells, as well as a few somatic stem cells, such as human urine …
pluripotent, and cancer stem cells, as well as a few somatic stem cells, such as human urine …
RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1α as critical for telomerase function in murine embryonic stem cells
M Coussens, P Davy, L Brown… - Proceedings of the …, 2010 - National Acad Sciences
In various types of stem cells, including embryonic stem (ES) cells and hematopoietic stem
cells, telomerase functions to ensure long-term self-renewal capacity via maintenance of …
cells, telomerase functions to ensure long-term self-renewal capacity via maintenance of …
Impact of mothers' age on telomere length and human telomerase reverse transcriptase expression in human fetal membrane-derived mesenchymal stem cells
GI Alrefaei, SA Alkarim… - Stem cells and …, 2019 - liebertpub.com
Age-related cellular changes and limited replicative capacity of adult mesenchymal stem
cells (MSCs) are few of the challenges confronting stem cell research. MSCs from human …
cells (MSCs) are few of the challenges confronting stem cell research. MSCs from human …
Telomerase inhibition promotes an initial step of cell differentiation of primate embryonic stem cell
T Maeda, R Kurita, T Yokoo, K Tani… - … and biophysical research …, 2011 - Elsevier
Embryonic stem (ES) cell is well known as a totipotent cell, which is derived from a blastcyst
and has potential to differentiate into every kind of somatic cell. ES cell bears self-renewal …
and has potential to differentiate into every kind of somatic cell. ES cell bears self-renewal …