We establish a novel method for the induction and collection of mesenchymal stem cells
using a typical cell surface marker, CD105, through adipogenesis from mouse ES cells. ES …

Following prolonged cell division, mesenchymal stem cells enter replicative senescence, a
state of permanent cell cycle arrest that constrains the use of this cell type in regenerative …

Mammalian aging of many tissues is associated with a decline in the replicative and
functional capacity of somatic stem cells. Understanding the basis of this decline is a major …

Peripheral blood-derived mesenchymal stem cells (PB-MSCs) show promise as a source of
cells for autologous transplantation because they can be harvested through minimally …

In vitro cultured autologous mesenchymal stem cells (MSCs) within passage 5 have been
approved for clinical application in stem cell-based treatment of cartilage defects. However …

Expression of telomerase activity presumably is involved in maintaining self-replication and
the undifferentiated state of stem cells. Adult mouse bone marrow mesenchymal stem cells …

Mesenchymal stem cells (MSCs) are of great therapeutic potentials due to their multilineage
differentiation capabilities. Before transplantation, in vitro culture expansion of MSCs is …

Bone-marrow-derived mesenchymal stem cells (MSCs) are multipotent cells capable of self-
renewal and differentiation into multiple cell types. Accumulating preclinical and clinical …

In this issue of Oncogene, Serakinci et al show that adult stem cells can be targets for
neoplastic transformation. After transducing human adult mesenchymal stem cells (hMSC) …

In cell transplantation therapy, mesenchymal stem cells (MSCs) are ideal seed cells due to
their easy acquisition and cultivation, strong regenerative capacity, multi-directional …