[HTML][HTML] Genetics of aging, health, and survival: dynamic regulation of human longevity related traits

AI Yashin, D Wu, LS Arbeeva, KG Arbeev… - Frontiers in …, 2015 - frontiersin.org
Background: The roles of genetic factors in human longevity would be better understood if
one can use more efficient methods in genetic analyses and investigate pleiotropic effects of …

Exonic variants in aging-related genes are predictive of phenotypic aging status

ME Breitbach, S Greenspan, NM Resnick… - Frontiers in …, 2019 - frontiersin.org
Background: Recent studies investigating longevity have revealed very few convincing
genetic associations with increased lifespan. This is, in part, due to the complexity of …

[PDF][PDF] 老龄健康的跨学科研究: 社会, 行为, 环境, 遗传因素及其交互作用

曾毅 - 中国卫生政策研究, 2012 - journal.healthpolicy.cn
Thisreviewarticlefirstdiscussesthatindividuals' lifespanandhealtharenotonlyassociatedwith
genetics, butalsomainlyaffectedbysocial, behavioral, andenvironmentalfactors; …

Genome-wide association study and linkage analysis of the healthy aging index

RL Minster, JL Sanders, J Singh… - … Series A: Biomedical …, 2015 - academic.oup.com
Abstract Background. The Healthy Aging Index (HAI) is a tool for measuring the extent of
health and disease across multiple systems. Methods. We conducted a genome-wide …

Genetics: Gene Expression

MML LEI, TKW Lee - Encyclopedia of Gerontology and Population Aging, 2022 - Springer
The Gateway to Global Aging Data (https://g2aging. org/) is a data and information platform
developed to facilitate longitudinal and crosscountry analyses on aging, especially those …

Whole-genome sequencing of Chinese centenarians reveals important genetic variants in aging WGS of centenarian for genetic analysis of aging

S Shen, C Li, L Xiao, X Wang, H Lv, Y Shi, Y Li… - Human Genomics, 2020 - Springer
Background Genetic research on longevity has provided important insights into the
mechanism of aging and aging-related diseases. Pinpointing import genetic variants …

Genomics of human health and aging

AM Kulminski, I Culminskaya - Age, 2013 - Springer
Despite notable progress of the candidate-gene and genome-wide association studies
(GWAS), understanding the role of genes contributing to human health and lifespan is still …

[HTML][HTML] Which Factors Influence Healthy Aging? A Lesson from the Longevity Village of Bama in China

W Zhang, Q Huang, Y Kang, H Li, G Tan - Aging and Disease, 2023 - ncbi.nlm.nih.gov
A growing aging population is associated with increasing incidences of aging-related
diseases and socioeconomic burdens. Hence, research into healthy longevity and aging is …

Genome-Wide Association Study

T Chung, LT Lau - Encyclopedia of Gerontology and Population Aging, 2022 - Springer
The Gateway to Global Aging Data (https://g2aging. org/) is a data and information platform
developed to facilitate longitudinal and crosscountry analyses on aging, especially those …

Design and analysis in genetic studies of human ageing and longevity

Q Tan, TA Kruse, K Christensen - Ageing research reviews, 2006 - Elsevier
With the success of the Human Genome Project and taking advantage of the recent
developments in high-throughput genotyping techniques as well as in functional genomics …