Why is aging conserved and what can we do about it?

JN Pitt, M Kaeberlein - PLoS biology, 2015 - journals.plos.org
The field of aging research has progressed rapidly over the past few decades. Genetic
modulators of aging rate that are conserved over a broad evolutionary distance have now …

Insights in molecular mechanisms of aging 2022

M Brotto, C Borrás - Frontiers in Aging, 2023 - frontiersin.org
We just completed the 2022 volume in September of 2023 with 9 articles and 56 authors and
we already have 4,154 downloads and over 16,000 views. These numbers offer a glimpse of …

[引用][C] 抗衰老研究进展

罗光, 王容 - 生理科学, 1988

Potential approaches for intervening aging

J Shen, GH Liu, M Song - National Science Open, 2022 - nso-journal.org
Though immortality and regeneration were ludicrous and far-fetched in an age of ignorance
and superstition, people have never stopped looking for the elixir of longevity. As a result of …

[图书][B] Clinical Genetics and Genomics of Aging

Medical care for older adults has long focused on preventing and treating chronic diseases
and the conditions that come with them. But now, researchers and clinicians hope a new …

[HTML][HTML] Conserved aging-related signatures of senescence and inflammation in different tissues and species

E Barth, A Srivastava, M Stojiljkovic, C Frahm… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Increasing evidence indicates that chronic inflammation and senescence are the cause of
many severe age-related diseases, with both biological processes highly upregulated …

Proteomics in aging research: A roadmap to clinical, translational research

R Moaddel, C Ubaida‐Mohien, T Tanaka… - Aging …, 2021 - Wiley Online Library
The identification of plasma proteins that systematically change with age and, independent
of chronological age, predict accelerated decline of health is an expanding area of research …

The expression signature of in vitro senescence resembles mouse but not human aging

K Wennmalm, C Wahlestedt, O Larsson - Genome biology, 2005 - Springer
Background The biological mechanisms that underlie aging have not yet been fully
identified. Senescence, a phenomenon occurring in vitro, limits the number of cell divisions …

[图书][B] Biology of longevity and aging: pathways and prospects

R Arking - 2019 - books.google.com
The latest edition of Robert Arking's seminal text on the biology of aging takes on an
extended title, since the field of gerontology has advanced to a point at which it is possible to …

Why do we grow old: is it because our cells just wear out, we run out of cells (or both), and what can we do about it?

JM Sedivy, JM van Deursen - Longevity & Healthspan, 2013 - Springer
Why do we grow old: is it because our cells just wear out, we run out of cells (or both), and what
can we do about it? | Longevity & Healthspan Skip to main content SpringerLink Account Menu …