To overcome loss of stem-like properties and spontaneous differentiation those hinder the
expansion and application of human mesenchymal stem cells (hMSCs), we have clonally …

Mesenchymal stem cells (MSCs) are bone marrow stroma-derived cells, which can
differentiate into several types of mesenchymal tissues. Although regarded as tissue-specific …

Human bone marrow mesenchymal stem cells (hMSC) represent a population of stem cells
that are capable of differentiation into multiple lineages. However, these cells exhibit …

Mesenchymal stem cells (MSCs) represent one of the most promising stem cells for a
number of degenerative conditions due to their multipotency, immunoprivileged properties …

Human bone marrow mesenchymal stem cells (hMSCs) are promising candidates for cell
therapy and tissue engineering. The life span of hMSCs during in vitro culture is limited …

Human mesenchymal stem cells (hMSCs) are expected to be an enormous potential source
for future cell therapy, because of their self-renewing divisions and also because of their …

Epigenetic regulation of gene expression by DNA methylation and histone modification
controls cell fate during development and homeostasis in adulthood. Aberrant epigenetic …

Human mesenchymal stem cells (hMSCs) can be readily isolated from bone marrow and
differentiate into multiple tissues, making them a promising target for future cell and gene …

Background Mesenchymal stem cells (MSCs) hold great promise for the treatment of difficult
diseases. As MSCs represent a rare cell population, ex vivo expansion of MSCs is …

Significant improvement in the understanding of mesenchymal stem cell (MSC) biology has
opened the way to their clinical use. However, concerns regarding the possibility that MSCs …