Oct4 轉錄調控網路參與肺癌惡化及抗藥性之機制探討
王憶卿 - 2016 - nckur.lib.ncku.edu.tw
科技部補助專題研究計畫成果報告Oct4 轉錄調控網路參與肺癌惡化及抗藥性之機制探討 Page
1 I 科技部補助專題研究計畫成果報告 期末報告 Oct4 轉錄調控網路參與肺癌惡化及抗藥性之 …
1 I 科技部補助專題研究計畫成果報告 期末報告 Oct4 轉錄調控網路參與肺癌惡化及抗藥性之 …
Oct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression
Background Oct4, a key stemness transcription factor, is overexpressed in lung cancer.
Here, we reveal a novel transcription regulation of long non-coding RNAs (lncRNAs) by …
Here, we reveal a novel transcription regulation of long non-coding RNAs (lncRNAs) by …
[引用][C] 全基因體分析顯示PTEN 及TNC 為Oct4 所調控肺癌惡化及抗藥性的新穎下游基因
湯硯安， 陳其欣， 孫孝芳， 程俊培， 曾新穆… - 成大研發 …, 2016 - nckur.lib.ncku.edu.tw
1 國立成功大學醫學院基礎醫學所, 2 藥理學研究所, 3 分子醫學研究所, 4 資訊工程學系, 5
醫學資訊研究所, 6 國立陽明大學急重症醫學研究所及臺北榮民總醫院胸腔外科, 7 …
醫學資訊研究所, 6 國立陽明大學急重症醫學研究所及臺北榮民總醫院胸腔外科, 7 …
Global Oct4 target gene analysis reveals novel downstream PTEN and TNC genes required for drug-resistance and metastasis in lung cancer
Overexpression of Oct4, a stemness gene encoding a transcription factor, has been reported
in several cancers. However, the mechanism by which Oct4 directs transcriptional program …
in several cancers. However, the mechanism by which Oct4 directs transcriptional program …
FOXC1-mediated LINC00301 facilitates tumor progression and triggers an immune-suppressing microenvironment in non-small cell lung cancer by regulating the …
CC Sun, W Zhu, SJ Li, W Hu, J Zhang, Y Zhuo… - Genome medicine, 2020 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are extensively intricate in the
tumorigenesis and metastasis of various cancer types. Nevertheless, the detailed molecular …
tumorigenesis and metastasis of various cancer types. Nevertheless, the detailed molecular …
Long noncoding RNA OIP5‐AS1 promotes the stemness of lung cancer cells through enhancing Oct4 mRNA stability
C Mao, X Li - Environmental Toxicology, 2022 - Wiley Online Library
Abstract Long noncoding RNA (lncRNA) OIP5‐AS1 was shown to facilitate drug resistance
and metastasis in several tumors. As cancer stem cells (CSCs) have been elucidated as the …
and metastasis in several tumors. As cancer stem cells (CSCs) have been elucidated as the …
[HTML][HTML] LncRNA HOXD-AS2 regulates miR-3681-5p/DCP1A axis to promote the progression of non-small cell lung cancer
Y Zhang, H Ma - Journal of Thoracic Disease, 2023 - ncbi.nlm.nih.gov
Background Non-small cell lung cancer (NSCLC) is the most common malignancy in lung
cancer, with a low survival rate and unfavorable prognosis. Dysregulated long non-coding …
cancer, with a low survival rate and unfavorable prognosis. Dysregulated long non-coding …
Downregulation of KPNA2 in non-small-cell lung cancer is associated with Oct4 expression
XL Li, LL Jia, MM Shi, X Li, ZH Li, HF Li… - Journal of translational …, 2013 - Springer
Background Oct4 is a major transcription factor related to stem cell self-renewal and
differentiation. To fulfill its functions, it must be able to enter the nucleus and remain there to …
differentiation. To fulfill its functions, it must be able to enter the nucleus and remain there to …
OIP5‑AS1 modulates epigenetic regulator HDAC7 to enhance non‑small cell lung cancer metastasis via miR‑140‑5p
J Mei, G Liu, W Wang, P Xiao, D Yang… - Oncology …, 2020 - spandidos-publications.com
Long non‑coding RNAs have been reported to be involved in non‑small cell lung cancer
(NSCLC) progression. However, whether Opa‑interacting protein 5 antisense RNA 1 (OIP5 …
(NSCLC) progression. However, whether Opa‑interacting protein 5 antisense RNA 1 (OIP5 …
Long noncoding RNASEH1‐AS1 exacerbates the progression of non‐small cell lung cancer by acting as a ceRNA to regulate microRNA‐516a‐5p/FOXK1 and …
C Zhang, J Huang, K Lou, H Ouyang - Cancer medicine, 2022 - Wiley Online Library
Background Till now, no study has focused on the functions of RNASEH1 antisense RNA 1
(RNASEH1‐AS1) in non‐small cell lung cancer (NSCLC). Accordingly, we measured the …
(RNASEH1‐AS1) in non‐small cell lung cancer (NSCLC). Accordingly, we measured the …