[HTML][HTML] Chronological age prediction based on DNA methylation: massive parallel sequencing and random forest regression

J Naue, HCJ Hoefsloot, ORF Mook… - Forensic science …, 2017 - Elsevier
The use of DNA methylation (DNAm) to obtain additional information in forensic
investigations showed to be a promising and increasing field of interest. Prediction of the …

DNA 甲基化与广西巴马地区长寿的相关性

李春宏, 黎湘娟, 陆华湘, 农清清, 覃健, 何敏, 张志勇 - 中国老年学杂志, 2015 - cqvip.com
目的探讨DNA 甲基化与巴马长寿的关系. 方法在广西巴马县长寿家族中选取60 例90~ 110
岁老人组成长寿组, 在非长寿家族中选取48~ 85 岁的健康者60 例组成对照组. 抽取外周血2 ml …

DNA 甲基化及其芯片技术研究进展

陈丽, 屈卫东 - 国外医学: 卫生学分册, 2007 - cqvip.com
DNA 甲基化是最早发现的, 最基本的表观遗传学机制. 大量研究表明DNA 甲基化与人类疾病有
密切关系. DNA 甲基化改变包括全基因组水平DNA 低甲基化和CpG 岛局部高甲基化. DNA …

[PDF][PDF] DNA 甲基化检测方法研究进展

代雅琪, 张博洋, 朱丽叶, 唐小革, 许文涛… - 农业生物技术 …, 2016 - journal05.magtech.org.cn
摘要DNA 甲基化一直是表观遗传学领域研究的重点之一. 研究表明, DNA
甲基化与胚胎发育以及肿瘤和疾病的发生, 发展密切相关, 因此, DNA 甲基化检测具有重要意义 …

DNA 甲基化在组织/体液来源鉴定中的研究进展

贾雲舒, 曹中围, 张文琼, 肖超, 韦甜, 易少华 - 中国法医学杂志, 2016 - cqvip.com
对可疑生物样本的组织/体液进行来源鉴别是重建犯罪现场, 推断犯罪性质等侦查活动中极为
重要的一环. 对表观遗传学理论的研究证明运用基因组中存在的组织特异性DNA …

Age-related DNA methylation analysis for forensic age estimation using post-mortem blood samples from Japanese individuals

X Guan, T Ohuchi, M Hashiyada, M Funayama - Legal Medicine, 2021 - Elsevier
As one of external visible characteristics (EVCs) in forensic phenotyping, age estimation is
essential to providing additional information about a sample donor. With the development of …

Age estimation based on DNA methylation using blood samples from deceased individuals

H Correia Dias, C Cordeiro… - Journal of forensic …, 2020 - Wiley Online Library
Age estimation using DNA methylation levels has been widely investigated in recent years
because of its potential application in forensic genetics. The main aim of this study was to …

DNA 甲基化与表型效应及环境因素相互关系

刘永哲, 于敏 - 中国公共卫生, 2015 - cqvip.com
DNA 甲基化作为表观遗传现象的分子基础由Holliday 和Pugh 于20 世纪70 年代发现.
表观遗传是指DNA 序列不发生变化但基因表达却发生了可遗传改变, 这些信息能经有丝分裂和 …

[HTML][HTML] DNA methylation-based age prediction from various tissues and body fluids

SE Jung, KJ Shin, HY Lee - BMB reports, 2017 - ncbi.nlm.nih.gov
Aging is a natural and gradual process in human life. It is influenced by heredity,
environment, lifestyle, and disease. DNA methylation varies with age, and the ability to …

DNA methylation: the future of crime scene investigation?

B Gršković, D Zrnec, S Vicković, M Popović… - Molecular biology …, 2013 - Springer
Proper detection and subsequent analysis of biological evidence is crucial for crime scene
reconstruction. The number of different criminal acts is increasing rapidly. Therefore, forensic …