The search for a reliable, early-disease biomarker for Parkinson's disease (PD) that reflects
underlying pathology is a high priority in PD research. Salivary alpha-synuclein (α-Syn) is an …

In Parkinson's disease (PD), alpha-synuclein (a-syn) can be detected in biological fluids
including saliva. Although previous studies found reduced a-syn total (a-syntotal) …

Introduction Alpha-synuclein (α-syn) aggregation is the pathological hallmark of Parkinson's
Disease (PD). In this study, we measured α-syn total (α-syn total), oligomeric α-syn (α-syn …

Introduction Lewy bodies are the pathological hallmarks of Parkinson's disease. There is a
need for effective biomarker that is cost effective, less invasive, and easily reproducible with …

Background Parkinson's disease (PD) is one of the most common degenerative diseases of
the central nervous system (CNS). Alpha-synuclein (A-syn) plays a critical role in the …

Parkinson's Disease (PD) is a common neurodegenerative disease which manifests with
motor features, such as bradykinesia, resting tremor, rigidity, and postural instability. Using …

The present study was to evaluate the diagnostic value of salivary total and oligomeric α-
synuclein levels in PD. Furthermore, we sought to explore the relationship between salivary …

Objective To date, there are no definitive biomarkers for diagnose Parkinson's disease (PD).
The detection of α-synuclein (α-Syn) in plasma of PD patients has yielded promising but …

Abstract Background Reliable biomarkers for Parkinson's disease (PD) diagnosis are
urgently needed. Alpha-synuclein (α-syn) and its proteoforms play a key role in PD …

Parkinson's disease (PD) is a common neurodegenerative disorder, characterized
pathologically by the presence of α‐synuclein (α‐syn)‐rich Lewy bodies. As clinical …