… 15 years, reversible protein acetylation … beyond transcription regulation. Here, we review
the progress accomplished during the past 50 years and discuss the future of protein acetylation…

… TETs to regulate diverse physiological functions 50 includes … understanding of the metabolic
link to gene regulation. Interestingly… that are perpetuated beyond restoration of normal blood …

… acetylation can encompass other types of protein acetylation, such as amino-terminal protein
acetylation and O-linked acetylation of … 50 . Proliferating cell nuclear antigen (PCNA) is also …

… Beyond histones, a large number of metabolic enzymes are … the cell to the regulation of
gene expression and metabolic pathways via the control of protein acetylation. Better knowledge …

… , tissue injury and metabolic stress. We propose a … acylation is regulated by the metabolism
of the different acyl-CoA forms, which in turn modulates the regulation of gene expression. …

… in the epigenetic regulation of gene expression will benefit from … Beyond these metabolic
transactions, acetyl-CoA serves as … Protein acetylation is a major posttranslational modification …

… These data suggest that metabolite levels might be contributing to the temporal control of
gene expression. This is supported by the observations that transient administration of …

… The research history of protein acetylation has spanned >50 years. Lysine … and
lysosome-related gene expression, can be acetylated by GCN5 at K274 and K279 in the way of Nε-…

… Recent studies have indicated that beyond sirtuins, the activity … acetyl-CoA may affect protein
acetylation. In this context, … DNA damage and changes in gene expression appear to have a …

… Protein acetylation and the regulation of cell growth Beyond its role in energy metabolism
and biosynthesis, acetyl-CoA also functions as the acetyl group donor for protein acetylation …