神经炎性疾病中的神经血管单元通透性: 一个共同的病理和治疗靶标?

M Monsour, CV Borlongan - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… Early blood-brain barrier (BBB) changes in MS involve reactive … Endothelial cells are
damaged via fibrinogen deposition and … of cell death such as oxidative stress, inflammation, and …

通过新的血脑屏障模型重建对阿尔茨海默病病理生理学的认识

K Matsuo, H Nshihara - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… stem cell-derived bloodbrain barrier models have been … in the brain parenchyma and
contributes to maintaining CNS … The plasma proteins that leak across the BBB, such as fibrinogen, …

凝血酶原克林格尔结构域-2, 小胶质细胞活化的介质: 阿尔茨海默病发病机制的新见解

JM Lee, SR Kim - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
… may be caused by blood-brain barrier (BBB) leakage. This … as thrombin and fibrinogen,
certainly contribute to neurotoxicity … hippocampi in vivo via oxidative stress. Int J Mol Sci 22:3486. …

基于纳米技术的基因治疗是治疗阿尔茨海默病的可靠工具

A Unnisa, NH Greig, MA Kamal - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… delivering therapeutic genes across the bloodbrain barrier. Nanotechnology has emerged …
leaky blood-brain barrier to fibrinogen contributes to oxidative damage in Alzheimers disease

响应衰老和神经炎症的小胶质细胞对神经退行性疾病的影响

T Han, Y Xu, L Sun, M Hashimoto, J Wei - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… factor beta (TGF-β), fibrinogen activator (PLAT), as well as matrix … parenchyma, forming a
blood-brain barrier (BBB) that … oxidative stress are not only important features of brain aging but …

[PDF][PDF] 脑小血管病相关免疫炎症机制研究进展

张海波, 郭燕军 - 中国现代神经疾病杂志, 2021 - cjcnn.org
… mechanisms such as bloodbrain barrier leakage, chronic … Oxidative stress in cerebral
small vessel disease: role of … Blood coagulation protein fibrinogen promotes autoimmunity …

小胶质细胞相关神经炎症可成为缺血性卒中的潜在治疗靶点

W Zhang, T Tian, SX Gong, WQ Huang… - 中国神经再生研究 …, 2021 - sjzsyj.com.cn
… neuroinflammation, oxidative stress, excitotoxicity, and destruction of the blood-brain barrier
(BBB) (… Subsequently, peripheral blood leukocytes, plasma fibronectin, fibrinogen and other …