诱导朊病毒蛋白脱落作为在大脑病理状态下神经保护和再生途径: 从理论到事实

A Matamoros-Angles, B Mohammadi, F Song… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
region localized within the flexible N-terminal tail, does not lead to more shedding but, instead,
to a strong … study discussed above further revealed that large ligands, such as IgGs (~150 …

半乳糖凝集素3 在神经炎症和神经退变中的新作用

BM Lozinski, K Ta, Y Dong - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… to a long non-lectin N-terminal domain, which enables it to bind … to an N-terminal tail composed
of the N-terminal segment (… This study also shows that the Gal3 CRD can directly interact …

[PDF][PDF] 病毒跨膜蛋白的结构功能与抗病毒药物设计

杨金华, 叶荣 - Journal of Microbes and Infection, 2009 - jmi.fudan.edu.cn
… The N-terminal domain of the murine coronavirus spike … S protein as revealed by pseudotype
virus bearing cleaved S … Potent neutralization of severe acute respiratory syndrome ( …

新型冠状病毒IgM-IgG 抗体检测试剂盒的制备及对15 例患者临床应用初试

李焕杰, 欧兰香, 陈虹, 陈健, 耿军… - 山东大学学报 …, 2020 - yxbwk.njournal.sdu.edu.cn
… -CoV-2 IgM-IgG antibodies by detecting serum of clinically confirmed patients. … domains
of S protein from SARS-CoV-2 virus were expressed and purified to prepare IgM-IgG antibody

新型冠状病毒受体结合结构域分子探针的构建及在中和抗体分离中的应用

王铮, 任莉, 杨馥榕, 玉敏, 胡彩琴… - China Tropical …, 2023 - search.ebscohost.com
… Western blot analysis revealed that the biotinylated probe … 编码4 种结构蛋白:刺突蛋白 (spike
protein, S),核衣壳蛋白(… S1可分为N末端结构域(N-terminal domain, NTD)和受体结合结 …

[PDF][PDF] 新型冠状病毒中和抗体研究进展

乔春霞, 王晶, 罗龙龙, 冯健男 - 中国药理学与毒理学杂志, 2021 - cjpt.magtechjournal.com
… S1 亚基又分为N 端结构域(N terminal domain,NTD)和受体… Potent binding of 2019 novel
coronavirus spike protein by a … individual reveals devel⁃ opment of potent neutralizing antibodies

[HTML][HTML] 新型冠状病毒的糖基化, 糖受体识别及糖链抑制剂的发现

喻伟艳, 许跃强, 李建军, 李志敏, 王琪, 杜昱光 - 生物工程学报, 2022 - cjb.ijournals.cn
… The development of vaccines, neutralizing antibodies, and … N端域(N-terminal domain,
NTD),受体结合域(receptor binding … binding domain of the SARS-CoV-2 spike protein and their …

[HTML][HTML] 刺突蛋白与新型冠状病毒的检测和治疗

咏竹陈, 峰邱 - Sheng Wu Yi Xue Gong Cheng Xue Za Zhi= Journal …, 2020 - ncbi.nlm.nih.gov
… In the past decades, spike protein has always been one of the most important objects in …
related to human life. In this review we introduce these research works related to spike proteins, …

[HTML][HTML] 两种严重急性呼吸综合征冠状病毒S 蛋白结构特征及抗原表位比较

LUN Yongzhi, LIU Ben, D Wen, SUN Jie… - Journal of Zhejiang …, 2020 - ncbi.nlm.nih.gov
… 氨基端结构域(N-terminal domain, NTD)和受体结合结构域(receptor-binding domain, RBD),
前者… Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane …

[HTML][HTML] 猪流行性腹泻病毒蛋白结构与功能的初探

茅翔, 任晓峰 - 世界华人消化杂志, 2013 - wjgnet.com
… PEDV与同类的TGEV,人冠状病毒NL63(human coronavirus NL63, HCoV-NL63)和人冠状病毒
… Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-…